Results 41 to 50 of about 650,298 (204)

Next⁃generation sequencing technology in the diagnosis of five patients with human herpesvirus encephalitis/meningitis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To evaluate the value of next⁃generation sequencing (NGS) of cerebrospinal fluid (CSF) in the diagnosis of human herpesvirus encephalitis/meningitis.
Ke JIN, Xiao-juan WANG, Hong-zhi GUAN, Ling-zhi QIN, Ya-zhen JIA, Ke-ke ZHOU, Hai-chang MA, Yue WANG, Fang WANG, Li XING, Wei LI   +10 more
doaj  

Equine herpesvirus 1 bridles T lymphocytes to reach its target organs [PDF]

, 2019
Equine herpesvirus 1 (EHV1) replicates in the respiratory epithelium and disseminates through the body via a cell-associated viremia in leukocytes, despite the presence of neutralizing antibodies. "Hijacked" leukocytes, previously identified as monocytic
Azab, Walid, Couck, Liesbeth, Favoreel, Herman, Laval, Kathlyn, Nauwynck, Hans, Poelaert, Katrien, Van Cleemput, Jolien, Van Den Broeck, Wim   +7 more
core   +1 more source

The activation of KSHV lytic cycle blocks autophagy in PEL cells [PDF]

, 2015
This study confirms that autophagy is activated concomitantly with KSHV lytic cycle induction, and that autophagy inhibition by BECN1 knockdown reduces viral lytic gene expression.
CIRONE, Mara, FAGGIONI, Alberto, FARINA, Antonella, Filardi, M, GONNELLA, ROBERTA, GRANATO, Marisa, SANTARELLI, Roberta, TORRISI, Maria Rosaria   +7 more
core   +1 more source

Regulation of alphaherpesvirus infections by the ICP0 family of proteins [PDF]

, 2013
Immediate-early protein ICP0 of herpes simplex virus type 1 (HSV-1) is important for the regulation of lytic and latent viral infection. Like the related proteins expressed by other alphaherpesviruses, ICP0 has a zinc-stabilized RING finger domain that ...
Boutell, Chris, Everett, Roger
core   +1 more source

Human Herpesvirus Sequencing in the Genomic Era: The Growing Ranks of the Herpetic Legion

Pathogens, 2019
The nine human herpesviruses are some of the most ubiquitous pathogens worldwide, causing life-long latent infection in a variety of different tissues. Human herpesviruses range from mild childhood infections to known tumour viruses and ‘trolls of ...
Charlotte J. Houldcroft
doaj   +1 more source

Kaposi’s Sarcoma-Associated Herpesvirus-Encoded circRNAs Are Expressed in Infected Tumor Tissues and Are Incorporated into Virions

mBio, 2020
Kaposi’s sarcoma-associated herpesvirus (KSHV) has recently been found to generate circular RNAs (circRNAs) from several KSHV genes, most abundantly from K10 (viral interferon regulatory factor 4 [vIRF4]), K7.3, and polyadenylated nuclear (PAN) RNA.
Bizunesh Abere, Jinghui Li, Hongzhao Zhou, Tuna Toptan, Patrick S. Moore, Yuan Chang   +5 more
doaj   +1 more source

Human herpesvirus 6 DNA was not detected in a brain specimen from a patient with mesial temporal sclerosis after status epilepticus due to human herpesvirus 6 infection

Epilepsia Open, 2022
We performed virological analysis of resected brain tissues from a patient with temporal lobe epilepsy associated with mesial temporal sclerosis after febrile status epilepticus caused by human herpesvirus 6 infection.
Yoshiki Kawamura, Satoshi Maesawa, Shingo Numoto, Ryuta Saito, Tetsushi Yoshikawa, Akihisa Okumura   +5 more
doaj   +1 more source

Biphasic euchromatin-to-heterochromatin transition on the KSHV genome following de novo infection. [PDF]

, 2013
The establishment of latency is an essential step for the life-long persistent infection and pathogenesis of Kaposi's sarcoma-associated herpesvirus (KSHV).
Brulois, Kevin, Izumiya, Yoshihiro, Jung, Jae U, Kung, Hsing-Jien, Lee, Hye-Ra, Tepper, Clifford, Toth, Zsolt   +6 more
core   +3 more sources

Modern data on the biology of Human Herpesvirus 6 and pathogenesis of Human Herpesvirus 6-associated clinical conditions (review of scientific publications)

Журнал инфектологии
Despite almost universal detection of human herpesvirus 6 in general population (up to 90% of individuals are considered seropositive), human herpesvirus 6-associated diseases remain poorly explored.
P. A. Drozdovskaya, V. A. Zinserling
doaj   +1 more source

DNA Sensors’ Signaling in NK Cells During HHV-6A, HHV-6B and HHV-7 Infection

Frontiers in Microbiology, 2020
ObjectivesThe host DNA sensor proteins TLR9, STING, IFI16 are central signaling molecules that control the innate immune response to cytosolic nucleic acids. Here we propose to investigate how Natural killer (NK) cell infection by human herpesvirus (HHV)-
Daria Bortolotti, Valentina Gentili, Elisabetta Caselli, Mariangela Sicolo, Irene Soffritti, Maria D’Accolti, Isabel Barao, Isabel Barao, Antonella Rotola, Dario Di Luca, Dario Di Luca, Roberta Rizzo   +11 more
doaj   +1 more source