Results 61 to 70 of about 619,898 (212)

Keratinocyte Priming by Staphylococcus aureus Reduces HSV‐1 Susceptibility

Allergy, EarlyView.
ADEH+ patients have a reduced microbial diversity with increased S. aureus and S. epidermidis colonization compared to ADEH− and healthy controls. Heat‐killed S. aureus reduced HSV‐1 susceptibility and release of infectious progeny virus in a keratinocyte in vitro model. Heat‐killed S.
Phila Cara Baumann, Rebecca Pospich, Katinka Döhner, Ilona Klug, Julio Cesar Villalvazo Guerrero, Jan Hartmann, Inken Harder, Wolfgang Lieb, Barbara Kind, Andreas Kleinheinz, Susanne Abraham, Matthias Augustin, Elke Weisshaar, Jochen Schmitt, Stephan Weidinger, Beate Sodeik, Thomas Werfel, Lennart M. Roesner, Stephan Traidl, The TREATgermany Study Group   +19 more
wiley   +1 more source

Key insights into biosecurity risks, communication preferences and behaviour change drivers among livestock transporters in Australia

Australian Veterinary Journal, EarlyView.
The transportation of livestock poses an increased risk of disease transmission, with transportation vehicles acting as vectors for disease. Biosecurity management within the livestock industry is therefore critical to reduce the risk of disease transmission. This study investigated the current biosecurity practices of stakeholders within the livestock
M Hernandez‐Jover, L Hayes, J Manyweathers, J Bond   +3 more
wiley   +1 more source

Specific RNA structures in the 5′ untranslated region of the human cytomegalovirus major immediate early transcript are critical for efficient virus replication

mBio
Human cytomegalovirus (HCMV) requires the robust expression of two immediate early proteins, IE1 and IE2, immediately upon infection to suppress the antiviral response and promote viral gene expression.
Bekah Dickmander, Andrew Hale, Wes Sanders, Erik Lenarcic, Ben Ziehr, Nathaniel J. Moorman   +5 more
doaj   +1 more source

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, EarlyView.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

Fatal Infection of a Pet Monkey with Human herpesvirus 1

Emerging Infectious Diseases, 2002
Concerns have been raised about pet monkeys as a potential threat to humans. We report the opposite situation, a danger to pets that arises from humans.
Hartwig P. Huemer, Clara Larcher, Thomas Czedik-Eysenberg, Norbert Nowotny, Martin Reifinger   +4 more
doaj   +1 more source

Clinical and genetic characterization of intellectual disability

Developmental Medicine &Child Neurology, EarlyView.
This study examines the etiological factors and comorbidities in a large cohort of Finnish patients with intellectual disability. Genetic causes—including chromosomal abnormalities and pathogenic gene variants—were more frequently identified in individuals with moderate to profound intellectual disability.
Aarni Venetvaara, Minna Kraatari‐Tiri, Jussi‐Pekka Tolonen, Marko Merikukka, IDGEN Study Group, Hannaleena Kokkonen, Teija Paakkola, Susanna Varis, Antti Dahl, Jarmo Körkkö, Jonna Komulainen‐Ebrahim, Jukka Moilanen, Johanna Uusimaa, Outi Kuismin, Elisa Rahikkala   +14 more
wiley   +1 more source

Outcomes of Kaposi sarcoma in people living with HIV who maintain long‐term viral suppression: A prospective case‐series

HIV Medicine, EarlyView.
Abstract Background Data on chemotherapeutic efficacy and tolerability for Kaposi Sarcomas (KS) in people living with HIV (PWH) and HIV‐virological control are limited. We aimed to describe clinical responses and tolerability of KS therapies in PWH with HIV‐aviraemic KS in a prospective cohort.
S. Bacquart, R. Palich, M. Veyri, S. Bregigeon‐Ronot, M.‐C. Picot, C. Vidal, L. Galicier, S. Choquet, J.‐P. Spano, M.‐A. Valantin, A. Makinson   +10 more
wiley   +1 more source

When to consider an inborn error of immunity: clues for physicians

Internal Medicine Journal, EarlyView.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

Commentary on: ”Pityriasis Rosea Recurrence is Much Higher than Previously Known: A Prospective Study”

Acta Dermato-Venereologica, 2019
is missing (Correspondence)
Francesco Drago, Giulia Ciccarese, Aurora Parodi   +2 more
doaj   +1 more source

Applicability of proposed diagnostic criteria of pityriasis rosea: Results of a prospective case-control study in India

Indian Journal of Dermatology, 2013
Background : The diagnosis of pityriasis rosea (PR) is generally clinical. Previous studies usually recruited relatively small numbers of patients and control subjects, leading to low power of study results. Systematic reviews and meta-analyses cannot be
Vijay Zawar, Antonio Chuh
doaj   +1 more source