Results 41 to 50 of about 655,601 (258)
Kaposi’s sarcoma-associated herpesvirus (KSHV) has recently been found to generate circular RNAs (circRNAs) from several KSHV genes, most abundantly from K10 (viral interferon regulatory factor 4 [vIRF4]), K7.3, and polyadenylated nuclear (PAN) RNA.
Bizunesh Abere +5 more
doaj +1 more source
Primary replication and invasion of the bovine gammaherpesvirus BoHV-4 in the genital mucosae [PDF]
Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus that is widespread in cattle. Ex vivo models with bovine genital tract mucosa explants were set up to study molecular/cellular BoHV-4-host interactions.
Bogado Pascottini, Osvaldo Américo +6 more
core +2 more sources
Human Herpesvirus Sequencing in the Genomic Era: The Growing Ranks of the Herpetic Legion
The nine human herpesviruses are some of the most ubiquitous pathogens worldwide, causing life-long latent infection in a variety of different tissues. Human herpesviruses range from mild childhood infections to known tumour viruses and ‘trolls of ...
Charlotte J. Houldcroft
doaj +1 more source
DNA Sensors’ Signaling in NK Cells During HHV-6A, HHV-6B and HHV-7 Infection
ObjectivesThe host DNA sensor proteins TLR9, STING, IFI16 are central signaling molecules that control the innate immune response to cytosolic nucleic acids. Here we propose to investigate how Natural killer (NK) cell infection by human herpesvirus (HHV)-
Daria Bortolotti +11 more
doaj +1 more source
Statistical properties of thermodynamically predicted RNA secondary structures in viral genomes
By performing a comprehensive study on 1832 segments of 1212 complete genomes of viruses, we show that in viral genomes the hairpin structures of thermodynamically predicted RNA secondary structures are more abundant than expected under a simple random ...
A. Tuplin +20 more
core +1 more source
A beta-herpesvirus with fluorescent capsids to study transport in living cells. [PDF]
Fluorescent tagging of viral particles by genetic means enables the study of virus dynamics in living cells. However, the study of beta-herpesvirus entry and morphogenesis by this method is currently limited.
Bauerfeind, Rudolf +11 more
core +4 more sources
We performed virological analysis of resected brain tissues from a patient with temporal lobe epilepsy associated with mesial temporal sclerosis after febrile status epilepticus caused by human herpesvirus 6 infection.
Yoshiki Kawamura +5 more
doaj +1 more source
A systematic review of the impact of psychosocial factors on immunity: Implications for enhancing BCG response against tuberculosis. [PDF]
Background: Tuberculosis (TB) remains an urgent global public health priority, causing 1.5 million deaths worldwide in 2018. There is evidence that psychosocial factors modulate immune function; however, how this may influence TB risk or BCG vaccine ...
Boccia, D +5 more
core +2 more sources
Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez +10 more
wiley +1 more source
Evidence for Tethering of Human Cytomegalovirus Genomes to Host Chromosomes
Tethering of viral genomes to host chromosomes has been recognized in a variety of DNA and RNA viruses. It can occur during both the productive cycle and latent infection and may impact viral genomes in manifold ways including their protection ...
Katrin Mauch-Mücke +3 more
doaj +1 more source

