Results 71 to 80 of about 570,023 (247)

Dendritic cells: Key players in human herpesvirus 8 infection and pathogenesis

Frontiers in Microbiology, 2014
Human herpesvirus 8 (HHV-8; Kaposi’s sarcoma-associated herpesvirus) is an oncogenic gammaherpesvirus that primarily infects cells of the immune and vascular systems.
Diana M. Campbell, Giovanna eRappocciolo, Frank J. Jenkins, Frank J. Jenkins, Charles R. Rinaldo, Charles R. Rinaldo   +5 more
doaj   +1 more source

Human Herpesvirus 8

Japanese Journal of Infectious Diseases, 2000
Human herpesvirus 8 ([HHV-8], Kaposi's sarcoma-associated herpesvirus [KSHV]) is a novel human oncovirus classified as a gamma-herpesvirus. HHV-8 is associated with Kaposi's sarcoma (KS), primary effusion lymphoma (PEL) and some cases of multicentric Castleman's disease (MCD). Antibodies against HHV-8 are detected in the sera of almost all KS patients,
H, Katano, T, Sata
openaire   +2 more sources

Immune involvement in neuropsychiatric disorders: Insights from single‐cell transcriptomic studies

Psychiatry and Clinical Neurosciences, EarlyView.
Neuropsychiatric disorders pose profound challenges to both research and treatment, largely due to their clinical heterogeneity and the limited understanding of their underlying biological mechanisms. While bulk RNA sequencing (bulk RNA‐seq) has been widely used to study gene expression, it cannot resolve cell‐type‐specific signals or detect rare ...
Tsutomu Takeda, Michihiro Toritsuka, Hiroto Tamakoshi, Nakao Iwata, Manabu Makinodan   +4 more
wiley   +1 more source

Kaposi sarcoma herpesvirus (KSHV) inflammatory cytokine syndrome (KICS): a case study

BMC Infectious Diseases
Background Kaposi sarcoma herpesvirus-inflammatory cytokine syndrome (KICS) is a rare, life-threatening condition associated with Kaposi sarcoma and systemic immune dysregulation induced by Human Herpesvirus 8 (HHV-8).
Ming Hong Choi, Ching See Leung, Laura Pui Yee To, Shui Wun Lai, Man Chun Chan, Thomas Shiu Hong Chik, Daphne Pui Ling Lau, Elaine Yuen Ling Au, Kwok Yung Yuen, Ivan Fan Ngai Hung, Tak Yin Tsang   +10 more
doaj   +1 more source

In vitro and in vivo human herpesvirus 8 infection of placenta.

PLoS ONE, 2008
Herpesvirus infection of placenta may be harmful in pregnancy leading to disorders in fetal growth, premature delivery, miscarriage, or major congenital abnormalities.
Mariantonietta Di Stefano, Maria Luisa Calabrò, Iole Maria Di Gangi, Santina Cantatore, Massimo Barbierato, Elisa Bergamo, Anfumbom Jude Kfutwah, Margherita Neri, Luigi Chieco-Bianchi, Pantaleo Greco, Loreto Gesualdo, Ahidjo Ayouba, Elisabeth Menu, Josè Ramòn Fiore   +13 more
doaj   +1 more source

Stewardship of Molecular Diagnostics in Transplant Viral Infections

Transplant Infectious Disease, EarlyView.
ABSTRACT The transplant environment requires special considerations when testing for viral infections as immunosuppression results in atypical infection profiles. Microbes otherwise considered commensals or causing mild disease can lead to severe infections in transplant environments. Therefore, guidelines tend to recommend broader microbial testing in
Scott Sugden, David Reynoso, Reema Mathew, Michael Loeffelholz   +3 more
wiley   +1 more source

Human Herpesvirus 8 Genotype E in Patients with Kaposi Sarcoma, Peru

Emerging Infectious Diseases, 2010
To determine human herpesvirus 8 (HHV-8) K1 genotypes in patients with Kaposi sarcoma (KS) from Peru, we characterized HHV-8 in 25 KS biopsy samples.
Olivier Cassar, Marie-Lise Blondot, Salim Mohanna, Gregory Jouvion, Francisco Bravo, Vicente Maco, Renan Duprez, Michel Huerre, Eduardo Gotuzzo, Antoine Gessain   +9 more
doaj   +1 more source

Human Herpesvirus 8--the First Human Rhadinovirus

JNCI Monographs, 1998
Kaposi's sarcoma (KS)-associated herpesvirus, also known as human herpesvirus 8 (HHV-8), is the first known human member of the genus Rhadinovirus. It is regularly found by polymerase chain reaction in all forms of KS, in certain types of Castleman's disease, and in body cavity-based B-cell lymphoma.
F, Neipel, J C, Albrecht, B, Fleckenstein   +2 more
openaire   +2 more sources

Acyclovir‐Resistant Herpes Simplex Virus in Pediatric Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant: A Case Series

Transplant Infectious Disease, EarlyView.
This retrospective case series of acyclovir‐resistant HSV infection in pediatric patients undergoing allogeneic HSCT discusses the clinical course, associated complications, and treatment, including side effects. We propose the first algorithm for investigating and managing acyclovir‐resistant HSV infections in pediatric HSCT recipients, highlighting ...
Jenna Nunn, Ahmed Ahmed, Srividhya Senthil, Oana Mirci‐Danicar, Denise Bonney, Claire Horgan, Omima Mustafa, Robert Wynn, Malcolm Guiver, Ramya Nataraj   +9 more
wiley   +1 more source

Human Herpesvirus 8 Induces Polyfunctional B Lymphocytes That Drive Kaposi’s Sarcoma

mBio, 2014
Kaposi’s sarcoma (KS) is an unusual neoplasia wherein the tumor consists primarily of endothelial cells infected with human herpesvirus 8 (HHV-8; Kaposi’s sarcoma-associated herpesvirus) that are not fully transformed but are instead driven to excess ...
Emilee R. Knowlton, Giovanna Rappocciolo, Paolo Piazza, Lauren M. Lepone, Sagar V. Nadgir, Arlene Bullotta, Stella J. Berendam, Jun Li, Todd A. Reinhart, Frank J. Jenkins, Charles R. Rinaldo   +10 more
doaj   +1 more source