Results 61 to 70 of about 610,373 (242)
Targeting of Prosurvival Pathways as Therapeutic Approaches against Primary Effusion Lymphomas: Past, Present, and Future [PDF]
, 2015 Constitutively activated prosurvival pathways render cancer cells addicted to their effects. Consequently they turn out to be the Achilles’ heels whose inhibition can be exploited in anticancer therapy.
CIRONE, Mara +6 more
core +4 more sources
Health Care Science, EarlyView.Findings indicate that within a standardized clinical pathway integrating structured immunosuppression, therapeutic drug monitoring, and early complication surveillance, liver transplantation after ICI exposure can be performed safely without increased rejection risk.
Ning Wang +14 more
wiley +1 more source
A rare histologic variant of Kaposi’s sarcoma
Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2023 An 80-year-old male presented with a 3-year history of progressive violaceous and edematous plaques on both hands. The remaining physical examination was unremarkable and systemic symptoms were absent.
Ana S. Pereira +3 more
doaj
Prevalence of human herpesvirus 8 infection in patients undergoing hemodialysis using nested-PCR
Journal of Acute Disease, 2019 Objective: To study the prevalence of HHV-8 infection in patients undergoing hemodialysis. Methods: In this study, blood samples of 89 patients undergoing hemodialysis were collected.
Somayeh Shokri +5 more
doaj +1 more source
The interplay between viral-derived miRNAs and host immunity during infection [PDF]
, 2019 MicroRNAs are short non-coding RNAs that play a crucial role in the regulation of gene expression during cellular processes. The host-encoded miRNAs are known to modulate the antiviral defense during viral infection.
Ingle, Harshad +3 more
core +1 more source
A Very Strong Enhancer Is Located Upstream of an Immediate Early Gene of Human Cytomegalovirus [PDF]
, 1985 A strong transcription enhancer was identified in the genomic DNA (235 kb) of human cytomegalovirus (HCMV), a ubiquitous and severe pathogen of the herpesvirus group.
Boshart, Michael +5 more
core +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.Thalassemia, a common hereditary blood disorder causing impaired globin synthesis and related complications, has seen remarkable progress in recent years due to advancements in genomics and molecular biology. Researchers have identified various gene variants related to thalassemia and improved clinical diagnostic methods, including new genetic testing ...
Chaoqiong Zhou +7 more
wiley +1 more source
HIV-negative disseminated Kaposi’s sarcoma in a Taiwanese patient
Kaohsiung Journal of Medical Sciences, 2011 Kaposi’s sarcoma is a common malignancy associated with HIV/AIDS. Herein, we describe the case of a 26-year-old man who presented with bilateral neck and inguinal lymphadenopathy, a massive tumor on the gum, and a nodule over the left eye.
Chiung-Tang Huang +4 more
doaj +1 more source
Human Herpesvirus 8-Encoded Cytokines [PDF]
Future Virology, 2010 Human herpesvirus (HHV)-8, also called Kaposi's sarcoma-associated herpesvirus, was discovered in 1994 and was rapidly sequenced, revealing several unique and surprising features of its genetic makeup. Among these discoveries was the identification of the first viral homolog of IL-6 and three CC/beta-chemokine ligands (viral CCL-1, -2 and -3), not ...
openaire +2 more sources
Journal of Clinical Laboratory Analysis, EarlyView.A 79‐year‐old man presented with massive pleural effusion in which cytological examination revealed lymphoma cells without evidence of a solid tumor mass. Negative EBV in situ hybridization and negative HHV8 and HIV testing, combined with flow cytometric immunophenotyping and molecular findings, supported a diagnosis of fluid overload–associated large ...
Van Vlierberghe Magalie +5 more
wiley +1 more source