Results 41 to 50 of about 610,373 (242)

Potential Application of the CRISPR/Cas9 System against Herpesvirus Infections. [PDF]

open access: yes, 2018
The CRISPR/Cas9 system has been applied in the genome editing and disruption of latent infections for herpesviruses such as the herpes simplex virus, Epstein⁻Barr virus, cytomegalovirus, and Kaposi's sarcoma-associated herpesvirus.
Chen, Yuan-Chuan   +3 more
core   +2 more sources

A Toolbox for Herpesvirus miRNA Research: Construction of a Complete Set of KSHV miRNA Deletion Mutants

open access: yesViruses, 2016
Kaposi’s sarcoma-associated herpesvirus (KSHV) encodes 12 viral microRNAs (miRNAs) that are expressed during latency. Research into KSHV miRNA function has suffered from a lack of genetic systems to study viral miRNA mutations in the context of the viral
Vaibhav Jain   +10 more
doaj   +1 more source

Human Herpesvirus 8: Current Issues [PDF]

open access: yesClinical Infectious Diseases, 2003
Although human herpesvirus 8 (HHV-8) is the etiologic agent of Kaposi sarcoma (KS), there are no formal guidelines for the clinical management of HHV-8 infection. In patients infected with human immunodeficiency virus (HIV), highly active antiretroviral therapy (HAART) is the best tool for the prevention of KS.
Michael J, Cannon   +2 more
openaire   +2 more sources

Clinical exuberance of classic Kaposi's sarcoma and response to radiotherapy [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2015
: Kaposi's sarcoma (KS) is a multicentric vascular neoplasm, with cutaneous and extracutaneous involvement. Different clinical and epidemiological variants have been identified.
Jeniffer Muñoz Trujillo   +5 more
doaj   +2 more sources

Oyster RNA-seq data support the development of Malacoherpesviridae genomics [PDF]

open access: yes, 2017
The family of double-stranded DNA (dsDNA) Malacoherpesviridae includes viruses able to infect marine mollusks and detrimental for worldwide aquaculture production. Due to fast-occurring mortality and a lack of permissive cell lines, the available data on
Rosani, Umberto, Venier, Paola
core   +2 more sources

Professional antigen presenting cells in human herpesvirus 8 infection

open access: yesFrontiers in Immunology, 2013
Professional antigen presenting cells (APC), i.e., dendritic cells, monocytes/macrophages, and B lymphocytes, are critically important in the recognition of an invading pathogen and presentation of antigens to the T cell-mediated arm of immunity.
Emilee R Knowlton   +7 more
doaj   +1 more source

An experimental evaluation of a loop versus a reference design for two-channel microarrays [PDF]

open access: yes, 2004
Motivation: Despite theoretical arguments that socalled "loop designs" of two-channel DNA microarray experiments are more efficient, biologists keep on using "reference designs".
C. P. Smith   +16 more
core   +2 more sources

HIV-associated lymphoma: A 5-year clinicopathologic study from India

open access: yesIndian Journal of Pathology and Microbiology, 2019
Context: Relative risk of non-Hodgkin lymphoma (NHL) in people living with HIV is 60–200 times that of normal population. This is the largest series from India on lymphomas arising in HIV-infected individuals including workup for Epstein–Barr virus (EBV)
Rajalakshmi Sampath   +4 more
doaj   +1 more source

The activation of KSHV lytic cycle blocks autophagy in PEL cells [PDF]

open access: yes, 2015
This study confirms that autophagy is activated concomitantly with KSHV lytic cycle induction, and that autophagy inhibition by BECN1 knockdown reduces viral lytic gene expression.
CIRONE, Mara   +7 more
core   +1 more source

Seroprevalence of Kaposi Sarcoma–associated Herpesvirus and Other Serologic Markers in the Brazilian Amazon

open access: yesEmerging Infectious Diseases, 2009
To determine the presence of Kaposi sarcoma–associated herpesvirus (KSHV) and other serologic markers, we tested serum specimens of 339 Amerindians, 181 rural non-Amerindians, and 1,133 urban blood donors (13 Amerindians) in the Brazilian Amazon.
Maria C. Nascimento   +10 more
doaj   +1 more source

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