Results 51 to 60 of about 820,674 (377)

Emergence of Resistant Human Immunodeficiency Virus Type 1 in Patients Receiving Fusion Inhibitor (T-20) Monotherapy

Antimicrobial Agents and Chemotherapy, 2002
The synthetic peptide T-20 (enfuvirtide) represents the first of a new class of antiretroviral compounds to demonstrate in vivo potency by targeting a step in viral entry.
Xiping Wei, J. Decker, Hongmei Liu, Zee Zhang, R. Arani, J. Kilby, M. Saag, Xiaoyun Wu, G. Shaw, J. Kappes   +9 more
semanticscholar   +1 more source

Hepatic peroxisome proliferator-activated receptor γ and α-mRNA expression in HCV-infected adults is decreased by HIV co-infection and is also affected by ethnicity

Clinics, 2015
OBJECTIVE: To determine peroxisome proliferator activated receptor α and γ mRNA expression in liver tissue of hepatitis C virus-infected patients with and without human immunodeficiency virus and its possible contribution to an acceleration of liver ...
Nathan J. Shores, Maria Cássia Mendes-Corrêa, Ivana Maida, JoLyn Turner, Kevin P. High, Sergio Babudieri, Marina Núãez   +6 more
doaj   +1 more source

XVir: A Transformer-Based Architecture for Identifying Viral Reads from Cancer Samples [PDF]

arXiv, 2023
It is estimated that approximately 15% of cancers worldwide can be linked to viral infections. The viruses that can cause or increase the risk of cancer include human papillomavirus, hepatitis B and C viruses, Epstein-Barr virus, and human immunodeficiency virus, to name a few.
arxiv  

Increased acute myocardial infarction rates and cardiovascular risk factors among patients with human immunodeficiency virus disease.

Journal of Clinical Endocrinology and Metabolism, 2007
CONTEXT Metabolic changes and smoking are common among HIV patients and may confer increased cardiovascular risk. OBJECTIVE The aim of the study was to determine acute myocardial infarction (AMI) rates and cardiovascular risk factors in HIV compared ...
V. Triant, Hang Lee, C. Hadigan, S. Grinspoon   +3 more
semanticscholar   +1 more source

Metal–Organic Framework‐Based Antimicrobial Touch Surfaces to Prevent Cross‐Contamination

Advanced Materials, EarlyView.
A MOF‐based antimicrobial door handle cover is developed. It completely inhibits the cross‐contamination of Gram‐positive bacterial species (Staphylococcus aureus, and Enterococcus faecalis), Gram‐negative bacterial species (Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii), and fungi (Candida albicans). Abstract Infection diseases
Javier Fonseca, Mary Cano‐Sarabia, Pilar Cortés, Jordi Saldo, David Montpeyó, Julia Lorenzo, Montserrat Llagostera, Inhar Imaz, Daniel Maspoch   +8 more
wiley   +1 more source

Current updates of CRISPR/Cas9‐mediated genome editing and targeting within tumor cells: an innovative strategy of cancer management

Cancer Communications, Volume 42, Issue 12, Page 1257-1287, December 2022., 2022
Abstract Clustered regularly interspaced short palindromic repeats‐associated protein (CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust, accurate, efficient and programmable method for genome targeting and editing. This innovative and revolutionary technique can play a significant role in animal modeling, in vivo genome
Khaled S. Allemailem, Mohammed A Alsahli, Ahmad Almatroudi, Faris Alrumaihi, Fahd Khaleefah Alkhaleefah, Arshad Husain Rahmani, Amjad Ali Khan   +6 more
wiley   +1 more source

Off‐The‐Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma

Advanced Materials, EarlyView.
A star‐shaped cross‐linked polyglutamate (StCl) nanocarrier delivers melanoma‐associated peptide antigens via redox‐responsive linkers, inducing lymph node‐targeted antigen presentation. The nanoconjugate activates dendritic cells, promotes effector T‐cell responses, and enables tumor regression even in humanized patient‐derived preclinical models ...
Liane IF Moura, Alessio Malfanti, Ana I Matos, Carina Peres, Ana Armiñán, Aroa Duro‐Castaño, Inmaculada Conejos‐Sánchez, María Medel, Snežana Đorđević, Paula Carrascosa, Bárbara Carreira, Rita C Acúrcio, Helena Xavier‐Ferreira, Alberto Hernández‐Barranco, Elena Castellano, Esther Roselló, José C. Machado, Héctor Peinado, María J. Vicent, Helena F. Florindo   +19 more
wiley   +1 more source

Seroprevalence and trend of human immunodeficiency virus among blood donors in Ethiopia: a systematic review and meta-analysis

BMC Infectious Diseases, 2019
Background Blood transfusion is one of the routine therapeutic interventions in hospitals that can be lifesaving. However, this intervention is related to several transfusion-related infections.
Henok Mulugeta, Getenet Dessie, Fasil Wagnew, Dube Jara, Cheru Tesema Leshargie, Ayenew Negesse   +5 more
doaj   +1 more source

Psychiatric disorders and drug use among human immunodeficiency virus-infected adults in the United States.

Archives of General Psychiatry, 2001
BACKGROUND There have been no previous nationally representative estimates of the prevalence of mental disorders and drug use among adults receiving care for human immunodeficiency virus (HIV) disease in the United States.
E. Bing, M. Burnam, D. Longshore, D. Longshore, J. Fleishman, C. Sherbourne, A. London, B. Turner, Ferd Eggan, Robin L. Beckman, B. Vitiello, Sally C. Morton, M. Orlando, S. Bozzette, S. Bozzette, Lucila Ortiz-Barron, M. Shapiro, M. Shapiro   +17 more
semanticscholar   +1 more source

Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors

Advanced Therapeutics, EarlyView.
Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe, Jacobus Burger, Jamie Jones, Apurva Panjla, William L. Murphy   +4 more
wiley   +1 more source