Results 61 to 70 of about 640,842 (298)

Dimerisation of HIV-2 genomic RNA is linked to efficient RNA packaging, normal particle maturation and viral infectivity. [PDF]

, 2007
BACKGROUND: Retroviruses selectively encapsidate two copies of their genomic RNA, the Gag protein binding a specific RNA motif in the 5' UTR of the genome.
Andrew ML Lever (60785), Anne L'Hernault (60782), Jane S Greatorex (60783), R Anthony Crowther (60784)   +3 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Management of a human immunodeficiency virus case with discordant antiviral drug resistance profiles in cerebrospinal fluid compared with plasma: a case report

Journal of Medical Case Reports, 2022
Background Human immunodeficiency virus-1-associated neurocognitive disorder is a known complication in individuals treated with antiretroviral therapy.
Didi Bang, Jannik Fonager, Isik Somuncu Johansen   +2 more
doaj   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Trends and spatial patterns of human immunodeficiency virus prevalence among men and women aged 15–49 in Sierra Leone: evidence from the 2008, 2013 and 2019 Demographic and Health Surveys

BMJ Global Health
Background Human immunodeficiency virus prevalence remains a major public health concern in Sierra Leone. This study examines the trends and spatial patterns of human immunodeficiency virus prevalence among men and women in Sierra Leone using data from ...
Wei Ma, Augustus Osborne, Lovel Fornah, Mulugeta Shegaze Shimbre   +3 more
doaj   +1 more source

Characterization of HIV-Associated Neurocognitive Impairment in Middle-Aged and Older Persons With HIV in Lima, Peru

Frontiers in Neurology, 2021
Background: With widespread use of antiretroviral medications, people living with HIV (PWH) are living longer worldwide, increasing their risk of developing neurocognitive impairment (NCI).
Monica M. Diaz, Monica M. Diaz, Monica M. Diaz, Marcela Gil Zacarías, Patricia Sotolongo, María F. Sanes, Donald J. Franklin, Donald J. Franklin, María J. Marquine, María J. Marquine, Mariana Cherner, Mariana Cherner, Cesar Cárcamo, Ronald J. Ellis, Ronald J. Ellis, Serggio Lanata, Serggio Lanata, Patricia J. García, Patricia J. García   +18 more
doaj   +1 more source

Finding the Fit: A Review of Three Intervention Models for Working with HIV/AIDS Impacted Substance Users who are Homeless [PDF]

, 1999
This report reflects research on three different models of services for people living with Human Immunodeficiency Virus (HIV) or Acquired Immunodeficiency Syndrome (AIDS) who are also low-income, substance users and are homeless or at risk of becoming ...
Amy Rynell, Maryann Mason
core  

THE CELLULAR RECEPTOR (CD4) OF THE HUMAN IMMUNODEFICIENCY VIRUS IS EXPRESSED ON NEURONS AND GLIAL CELLS IN HUMAN BRAIN [PDF]

, 1987
The peculiar tropism of the human immunodeficiency virus (HIV) for T helper lymphocytes can be explained by a specific interaction between the virus and the CD4 molecule on these cells (1, 2).
Funke, Ilona, Hahn, Alfred, Rieber, Ernst Peter, Riethmüller, Gert, Weiss, Elisabeth H.   +4 more
core   +1 more source

A case of acanthosis nigricans in a HIV-infected patient [PDF]

, 2020
Background: To date, very little information is available concerning the relationship between acanthosis nigricans (AN) and infection with human immunodeficiency virus type 1 (HIV-1).
De Vincentiis, Ludovica, Di Paolo, Marcello, Iacovelli, Alessandra, Mezzaroma, Ivano, Palange, Paolo, Soda, Giuseppe   +5 more
core   +1 more source

Human immunodeficiency virus & cardiovascular risk

The Indian Journal of Medical Research, 2011
Highly active antiretroviral therapy (HAART) significantly changed the prevalence of the cardiovascular manifestations of human immunodeficiency virus (HIV)/AIDS. In developed countries, a 30 per cent reduction in the prevalence of cardiomyopathy and pericardial effusion was observed, possibly related to a reduction of opportunistic infections and ...
Barbaro, Giuseppe, Barbarini, Giorgio
openaire   +2 more sources