Results 101 to 110 of about 422,759 (353)

Model‐based evaluation of the interaction between ritonavir‐boosted atazanavir and rifampicin in Ugandan adults with HIV

British Journal of Clinical Pharmacology, EarlyView.
Aim Concomitant treatment of tuberculosis (TB) and human immunodeficiency virus (HIV) is complicated by drug‐drug interactions (DDI). This analysis aimed to characterize the DDI between ritonavir‐boosted atazanavir (ATV/r) and rifampicin in plasma and peripheral blood mononuclear cells (PBMC).
Allan Kengo, Juan Eduardo Resendiz‐Galvan, Letisha Najjemba, Henry Mugerwa, Amedeo De Nicolò, Antonio D'Avolio, Shakir Atoyebi, Lubbe Wiesner, Elin M. Svensson, Catriona Waitt, Paolo Denti   +10 more
wiley   +1 more source

False positive fourth generation HIV test in a patient with severe malaria

International Journal of Infectious Diseases, 2019
Severe malaria is an uncommon diagnosis in the United States. However, awareness of signs, symptoms, and treatment options is imperative in order to promptly initiate optimal therapy.
Jessica M. Stempel, Andres L. Mora Carpio, Daniel Puga, Sarah Perloff   +3 more
doaj   +1 more source

Failure of dideoxynucleosides to inhibit human immunodeficiency virus replication in cultured human macrophages. [PDF]

, 1987
Primary human monocyte-derived macrophages (MDM) were shown to have diminished deoxynucleoside kinase activities compared to T lymphoblasts, and a reduced ability to phosphorylate dideoxynucleosides with anti-human immunodeficiency virus (HIV) activity ...
Carson, DA, Kornbluth, RS, Richman, DD
core  

Is HIV-1 RNA dimerization a prerequisite for packaging? Yes, no, probably? [PDF]

, 2004
During virus assembly, all retroviruses specifically encapsidate two copies of full-length viral genomic RNA in the form of a non-covalently linked RNA dimer.
Liang, Chen, Russell, Rodney S, Wainberg, Mark A   +2 more
core   +3 more sources

Adverse drug reactions, particularly liver disorders, drive interruptions in anti‐tuberculosis treatment: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aims Adverse drug reactions (ADRs) are a key driver of missed doses of anti‐tuberculosis (TB) therapy. We aimed to determine the relative burden of ADR‐driven missed doses, the missed dose patterns associated with ADRs, and the association between specific ADRs and missed doses.
Eleanor G. Dixon, Evita Biraua, Edvards Brencsēns, Vitālijs Pašuks, Vija Riekstina, Anete Šperberga, Marisa D. Muckian, James W. Dear, Liga Kuksa, Derek J. Sloan, Helen R. Stagg   +10 more
wiley   +1 more source

Effects of traumatic brain injury on cognitive functioning and cerebral metabolites in HIV-infected individuals. [PDF]

, 2011
We explored the possible augmenting effect of traumatic brain injury (TBI) history on HIV (human immunodeficiency virus) associated neurocognitive complications.
Atkinson, J Hampton, CHARTER group, Clifford, David, Collier, Ann C, Ellis, Ronald J, Fennema-Notestine, Christine, Franklin, Donald, Gelman, Benjamin, Grant, Igor, Heaton, Robert, Jernigan, Terry, Lin, Kenny, Marra, Christina, McArthur, Justin, McCutchan, Allen, Morgello, Susan, Simpson, David, Taylor, Michael J   +17 more
core   +3 more sources

Endogenous Retrovirus‐Like Particle‐Deficient CHO Cells Can be Generated by CRISPR or shRNA and Enriched Based on Cell‐Surface Expression of Retroviral Envelope Protein

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Despite evidence that they are not functional or infective, retrovirus‐like particles (RVLPs), originating from endogenous proviral sequences in Chinese hamster ovary (CHO) cells, present a safety risk for biotherapeutics manufactured using this cell line due to their resemblance to other mammalian leukemia viruses.
Matthew Stuible, Sergio P. Alpuche‐Lazcano, Christian Gervais, Manon Ouimet, Julie Lippens, Martine Pagé, Audrey Morasse, Anna N. Moraitis, Yves Durocher   +8 more
wiley   +1 more source

Human immunodeficiency virus prevention and testing strategies among men who have sex with men in the UK: the PANTHEON research programme including the SELPHI RCT

Programme Grants for Applied Research
Background Rates of human immunodeficiency virus diagnoses in UnitedKingdom men who have sex with men were at a 10-year high in 2014; many recent infections indicated ongoing transmission. There was a need to increase testing rates, reduce late diagnosis
Janey Sewell, T Charles Witzel, David Dunn, Fiona Lampe, Fiona Burns, Peter Weatherburn, Sheena McCormack, Leanne McCabe, Alec Miners, Valentina Cambiano, Roger Pebody, Roy Trevelion, Nadia Hanum, Andrew Phillips, Alison Rodger   +14 more
doaj   +1 more source

Tp–e interval and Tp–e/QT ratio in patients with Human Immunodeficiency Virus

Journal of Infection and Public Health, 2018
Human Immunodeficiency Virus (HIV) infection and AIDS are known to cause cardiovascular diseases such as premature coronary artery disease, cardiomyopathy, and arrhythmias.
Sefa Ünal, Çağrı Yayla, Burak Açar, Ahmet G. Ertem, Mehmet K. Akboğa, Serkan Gökaslan, Mehmet A. Erdöl, Meliha Ç. Sönmezer, Esra Kaya Kiliç, Çiğdem Ataman Hatipoğlu, Necla Tulek, Fatma S. Erdinç, Sinan Aydoğdu, Ahmet Temizhan   +13 more
doaj   +1 more source

The Role of Follicular Dendritic Cells in Human Immunodeficiency Virus Pathogenesis [PDF]

, 1995
Infection with Human Immunodeficiency Virus-1(HIV) results in a disease process characterized by three stages: an acute phase characterized by viremia, a clinically latent stage with little or no detection of virus in the blood, and the last stage, AIDS,
Heath, Sonya Lynn
core   +1 more source