Mining Alzheimer's Interactomes, Macromolecular Complexes and Pathways for Drug Discovery
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia. Many cases are diagnosed annually and there is no currently available cure. Understanding the underlying disease biology of AD through the study of molecular networks, particularly by mapping clinical variants to tissue‐specific interactomes and ...
Kalpana Panneerselvam+12 more
wiley +1 more source
Toxoplasmosis and human immunodeficiency virus (HIV) disease [PDF]
R.E. Holliman, Linda C. New
openaire +3 more sources
A human immunodeficiency virus type 1 (HIV-1)-based retroviral vector system utilizing stable HIV-1 packaging cell lines [PDF]
Richard G. Carroll+5 more
openalex +1 more source
Fc receptors for IgG (Fc gamma Rs) on human monocytes and macrophages are not infectivity receptors for human immunodeficiency virus type 1 (HIV-1): studies using bispecific antibodies to target HIV-1 to various myeloid cell surface molecules, including the Fc gamma R. [PDF]
Ruth I. Connor+5 more
openalex +1 more source
This review explores improved tetracycline (TCN) delivery via polymer‐based nanocarriers to enhance solubility, stability, and targeted release. It also covers stimuli‐responsive systems, triggered by pH, enzymes, or reactive oxygen species (ROS), and co‐delivery approaches that increase therapeutic efficacy in cancer and inflammatory diseases ...
Mahsa Molaei Nasr+5 more
wiley +1 more source
Association of hepatitis B surface antigen and core antibody with acquisition and manifestations of human immunodeficiency virus type 1 (HIV-1) infection. [PDF]
Rachel Solomon+6 more
openalex +1 more source
Opsoclonus‐Myoclonus: Not Always Paraneoplastic
Movement Disorders Clinical Practice, EarlyView.
Fernanda Lustosa Cabral Gomez+4 more
wiley +1 more source
Advancing pharmacometrics in Africa—Transition from capacity development toward job creation
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai+10 more
wiley +1 more source
How does HIV-1 Infect a Susceptible Human Cell? : Current thinking
To insure its survival, the human immunodeficiency virus (HIV), the causative agent of acquired immunodeficiency syndrome (AIDS), utilises more than one gate to enter a target cell.
Ali A. Al-Jabri
doaj