Results 311 to 320 of about 556,307 (406)

The Spectrum of Epidermolysis Bullosa in KwaZulu‐Natal, South Africa

open access: yesInternational Journal of Dermatology, EarlyView.
ABSTRACT Background Epidermolysis bullosa (EB) is a rare, heterogeneous genodermatosis characterized by skin fragility due to inherited defects in genes encoding proteins that maintain epidermal–dermal integrity. The severity and complications of EB vary by subtype, and no cure currently exists. The epidemiology is unknown in South Africa. Methods This
Antoinette Chateau   +10 more
wiley   +1 more source

Sketching T cell atlases in the single‐cell era: challenges and recommendations

open access: yesImmunology &Cell Biology, EarlyView.
Recent advances in single‐cell technologies have enabled the creation of T cell atlases, providing detailed maps of adaptive immunity across tissues, development and disease states. These atlases help uncover T cell diversity, functional states and disease mechanisms, aiding in the identification of therapeutic targets.
Itana Bojović   +3 more
wiley   +1 more source

Clinical characteristics and treatment of varicella zoster virus central nervous system infection in an Australian tertiary hospital

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background and Aim Varicella zoster virus (VZV) is a neurotropic herpesvirus. With improved access to molecular diagnostics, there is increasing recognition of VZV with central nervous system involvement. This study aimed to describe the demographic, clinical and treatment characteristics of patients admitted to an Australian tertiary hospital
Connie Lam   +6 more
wiley   +1 more source

Increased CD8dim and Decreased CD8bright T Cells as Immunological Signature for Multibacilary Leprosy Patients

open access: yesImmunology, EarlyView.
Leprosy, a chronic infectious disease caused by Mycobacterium leprae, manifests in a spectrum of clinical forms and severity. This study investigated the percentage of CD8+ T cells and their subpopulations (CD8bright and CD8dim T cells) in leprosy patients stratified by clinical forms, bacterial load, and age.
Yuri Scheidegger de Castro   +7 more
wiley   +1 more source

Prevalence and Treatment Outcomes of Syphilis among People with Human Immunodeficiency Virus (HIV) Engaging in High-Risk Sexual Behavior: Real World Data from Northern Greece, 2019-2022. [PDF]

open access: yesMicroorganisms
Nanoudis S   +11 more
europepmc   +1 more source

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

open access: yesImmunology, EarlyView.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder   +4 more
wiley   +1 more source

Cancer risk among people living with Human Immunodeficiency Virus (HIV) in Rwanda from 2007 to 2018. [PDF]

open access: yesInt J Cancer
Dusingize JC   +11 more
europepmc   +1 more source

Should We Advance Our Understanding of Immunoglobulin E in Viral Immunity?

open access: yesImmunology, EarlyView.
Immunoglobulin E has been extensively studied in allergies and parasitic diseases. Antigen‐specific IgE has been identified as part of the humoral response to viruses. This revision speculates on possible functionalities for IgE, such as neutralisation, cytotoxicity and immunopathology of viral diseases, and provide insights about gaps to fill in ...
Amanda Izeli Portilho   +3 more
wiley   +1 more source

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