Results 311 to 320 of about 556,307 (406)

The Spectrum of Epidermolysis Bullosa in KwaZulu‐Natal, South Africa

International Journal of Dermatology, EarlyView.
ABSTRACT Background Epidermolysis bullosa (EB) is a rare, heterogeneous genodermatosis characterized by skin fragility due to inherited defects in genes encoding proteins that maintain epidermal–dermal integrity. The severity and complications of EB vary by subtype, and no cure currently exists. The epidemiology is unknown in South Africa. Methods This
Antoinette Chateau, Thirona Naicker, Cassandra Bruce‐Brand, Johann Schneider, Colleen Aldous, Ncoza Dlova, Hui‐Ching Cheng, Pei‐Chi Lin, Hsin‐Yu Huang, Chao‐Kai Hsu, John A. McGrath   +10 more
wiley   +1 more source

Hypercalcemia as a rare manifestation of immune reconstitution inflammatory syndrome (IRIS) in a person living with Human Immunodeficiency Virus (HIV) with disseminated nontuberculous mycobacteriosis. [PDF]

Infection
Webendoerfer M, Konik M, Zettler M, Wienker J, Rawitzer J, Esser S, Kehrmann J, Herrmann K, Reinhardt HC, Witzke O, Dolff S.   +10 more
europepmc   +1 more source

Sketching T cell atlases in the single‐cell era: challenges and recommendations

Immunology &Cell Biology, EarlyView.
Recent advances in single‐cell technologies have enabled the creation of T cell atlases, providing detailed maps of adaptive immunity across tissues, development and disease states. These atlases help uncover T cell diversity, functional states and disease mechanisms, aiding in the identification of therapeutic targets.
Itana Bojović, António GG Sousa, Sini Junttila, Laura L Elo   +3 more
wiley   +1 more source

Clinical characteristics and treatment of varicella zoster virus central nervous system infection in an Australian tertiary hospital

Internal Medicine Journal, EarlyView.
Abstract Background and Aim Varicella zoster virus (VZV) is a neurotropic herpesvirus. With improved access to molecular diagnostics, there is increasing recognition of VZV with central nervous system involvement. This study aimed to describe the demographic, clinical and treatment characteristics of patients admitted to an Australian tertiary hospital
Connie Lam, Eve Chen, Arthur Thevathasan, Terry Yan, Michael Moso, Joe Sasadeusz, Stephen Muhi   +6 more
wiley   +1 more source

Human Herpesvirus-8 (HHV-8)-Positive Human Immunodeficiency Virus (HIV)-Negative Multicentric Castleman Disease With a Fulminant Course. [PDF]

Cureus
Brito MT, Amador AF, Moço Coutinho R, Ribeiro A, Almeida JS.   +4 more
europepmc   +1 more source

Increased CD8dim and Decreased CD8bright T Cells as Immunological Signature for Multibacilary Leprosy Patients

Immunology, EarlyView.
Leprosy, a chronic infectious disease caused by Mycobacterium leprae, manifests in a spectrum of clinical forms and severity. This study investigated the percentage of CD8+ T cells and their subpopulations (CD8bright and CD8dim T cells) in leprosy patients stratified by clinical forms, bacterial load, and age.
Yuri Scheidegger de Castro, Letícia Silva Nascimento, Juliana Azevedo da Silva, Rebeka da Conceição Souza, Gabriel Nogueira Araújo, Sandra Chalhub de Oliveira, Edilbert Pellegrini Nahn Junior, Alba Lucínia Peixoto‐Rangel   +7 more
wiley   +1 more source

Prevalence and Treatment Outcomes of Syphilis among People with Human Immunodeficiency Virus (HIV) Engaging in High-Risk Sexual Behavior: Real World Data from Northern Greece, 2019-2022. [PDF]

Microorganisms
Nanoudis S, Pilalas D, Tziovanaki T, Constanti M, Markakis K, Pagioulas K, Papantoniou E, Kapiki K, Chrysanthidis T, Kollaras P, Metallidis S, Tsachouridou O.   +11 more
europepmc   +1 more source

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

Immunology, EarlyView.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder, Md. Mijanur Rahman, Md. Sifat Rahi, Dean L. Pountney, Ming Q. Wei   +4 more
wiley   +1 more source

Cancer risk among people living with Human Immunodeficiency Virus (HIV) in Rwanda from 2007 to 2018. [PDF]

Int J Cancer
Dusingize JC, Murenzi G, Muhoza B, Businge L, Remera E, Uwinkindi F, Hagenimana M, Rwibasira G, Nsanzimana S, Castle PE, Anastos K, Clifford GM.   +11 more
europepmc   +1 more source

Should We Advance Our Understanding of Immunoglobulin E in Viral Immunity?

Immunology, EarlyView.
Immunoglobulin E has been extensively studied in allergies and parasitic diseases. Antigen‐specific IgE has been identified as part of the humoral response to viruses. This revision speculates on possible functionalities for IgE, such as neutralisation, cytotoxicity and immunopathology of viral diseases, and provide insights about gaps to fill in ...
Amanda Izeli Portilho, Valéria Oliveira Silva, Luis Fernando de Macedo Brigido, Elizabeth De Gaspari   +3 more
wiley   +1 more source