In silico model of infection of a CD4(+) T-cell by a human immunodeficiency type 1 virus, and a mini-review on its molecular pathophysiology [PDF]
arXiv, 2021 Introduction. Can the infection due to the human immunodeficiency virus type 1 induce a change in the differentiation status or process in T cells?. Methods. We will consider two stochastic Markov chain models, one which will describe the T-helper cell differentiation process, and another one describing that process of infection of the T-helper cell by
arxiv
Modeling HIV-1 infection in the brain.
PLoS Computational Biology, 2020 While highly active antiretroviral therapy (HAART) is successful in controlling the replication of Human Immunodeficiency Virus (HIV-1) in many patients, currently there is no cure for HIV-1, presumably due to the presence of reservoirs of the virus. One
Colin T Barker, Naveen K Vaidya
doaj +1 more source
SIV/SHIV-Zika co-infection does not alter disease pathogenesis in adult non-pregnant rhesus macaque model. [PDF]
PLoS Neglected Tropical Diseases, 2018 Due to the large geographical overlap of populations exposed to Zika virus (ZIKV) and human immunodeficiency virus (HIV), understanding the disease pathogenesis of co-infection is urgently needed.
Mehdi R M Bidokhti +6 more
doaj +1 more source
IDCases, 2019 We present a case of a man infected with human immunodeficiency virus (HIV) and who was diagnosed with Cytomegalovirus (CMV) colitis shortly after initiation of antiretroiviral therapy (ART).
Shinji Yoshida +2 more
doaj
Conformational HIV-1 Envelope on particulate structures: a tool for chemokine coreceptor binding studies [PDF]
, 2010 The human immunodeficiency virus type 1 (HIV-1) external envelope glycoprotein gp120 presents conserved binding sites for binding to the primary virus receptor CD4 as well as the major HIV chemokine coreceptors, CCR5 and ...
Buonaguro, Franco M +3 more
core +4 more sources
A model of HIV budding and self-assembly, role of cell membrane [PDF]
, 2008 Budding from the plasma membrane of the host cell is an indispensable step in the life cycle of the Human Immunodeficiency Virus (HIV), which belongs to a large family of enveloped RNA viruses, retroviruses. Unlike regular enveloped viruses, retrovirus budding happens {\em concurrently} with the self-assembly of retrovirus protein subunits (Gags) into ...
arxiv +1 more source
Toward a Macaque Model of HIV-1 Infection: Roadblocks, Progress, and Future Strategies
Frontiers in Microbiology, 2020 The human-specific tropism of Human Immunodeficiency Virus Type 1 (HIV-1) has complicated the development of a macaque model of HIV-1 infection/AIDS that is suitable for preclinical evaluation of vaccines and novel treatment strategies.
Rajesh Thippeshappa +2 more
doaj +1 more source
True story about HIV: theory of viral sequestration and reserve infection
HIV/AIDS: Research and Palliative Care, 2011 Simon Situma BarasaKenya Polytechnic University College, Nairobi, KenyaAbstract: Radical cure of infectious disease lies in the principle that the contagion is eliminated and its propagation within the body is stopped.
Barasa S
doaj
Epidemiology of Severe Acute Respiratory Illness and Risk Factors for Influenza Infection and Clinical Severity among Adults in Malawi, 2011-2013 [PDF]
, 2018 Data on the epidemiology of severe acute respiratory illness (SARI) in adults from low-income, high human immunodeficiency virus (HIV) prevalence African settings are scarce. We conducted adult SARI surveillance in Blantyre, Malawi.
Albrich +48 more
core +4 more sources
Complex Agent Networks explaining the HIV epidemic among homosexual men in Amsterdam [PDF]
arXiv, 2008 Simulating the evolution of the Human Immunodeficiency Virus (HIV) epidemic requires a detailed description of the population network, especially for small populations in which individuals can be represented in detail and accuracy. In this paper, we introduce the concept of a Complex Agent Network(CAN) to model the HIV epidemics by combining agent ...
arxiv