The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Socioeconomic, Institutional & Political Determinants of Human Rights Abuse: A Subnational Study of India, 1993-2002 [PDF]
, 2008 We conduct an econometric analysis of socioeconomic, institutional and political factors determining government respect for human rights within India.
Vadlamannati, Krishna Chaitanya
core +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Land use in the tropical karst - the case of Peruaçu, Januària and Jaiba; SE Brazil. [PDF]
International Journal of Speleology, 1999 The karstic regions of the municipalities of Peruaçu, Januària and Jaiba present a variety of soil uses which are a function of the organization of the karstic relief.
Kohler Heinz Charles +2 more
doaj
Nepal: Earthquake Recovery Must Safeguard Human Rights [PDF]
, 2015 This briefing highlights some important areas of concern which Amnesty International believes could have an impact on the success of relief and reconstruction endeavours in Nepal.Protection and respect for human rights has been severely weakened by Nepal'
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Biological Activity of Mountain Soils of the Western Caucasus after Deforestation
Лесной журналA study of a set of indicators characterizing the ecological state of forest soils in the mountains of the North-Western Caucasus under broad-leaved and mixed forests has been conducted.
Aslan K. Shkhapatsev +5 more
doaj +1 more source
Human exposure in low Earth orbit [PDF]
Human exposure to trapped electrons and protons in low Earth orbit (LEO) is evaluated on a basis of a simple approximation of the human geometry for spherical shell shields of varying thickness.
Cucinotta, F., Wilson, J. W.
core +1 more source
Paying for Overhead: A Study of the Impact of Foundations' Overhead Payment Policies on Educational and Human Service Organizations [PDF]
, 2007 Examines the impact of foundations' overhead funding policies on educational and human services organizations, using data from two original surveys and six case ...
Heidi K. Frederick, Patrick Rooney
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