Results 41 to 50 of about 556,928 (218)

A speech-driven embodied entrainment character system for supporting line-of-sight interaction using an interaction-activated communication model

Nihon Kikai Gakkai ronbunshu, 2016
Line-of-sight such as gaze and eye-contract plays an important role to enhance the embodied interaction and communication through avatars. In addition, many eyeball movement models and communication systems using avatars with the line-of-sight have been ...
Yoshihiro SEJIMA, Koki ONO, Tomio WATANABE   +2 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Study on the biped walking pet robot with short legs (2nd report: Pet robots for the reminiscence therapy)

Nihon Kikai Gakkai ronbunshu, 2018
Along with the extreme aging of the population in Japan, the number of elderly with dementia has been increasing. Measures to address their symptoms and suppress the onset of dementia have been demanded.
Yuichi NAKAZATO, Kenta KYOJIMA, Kensuke TAKITA, Masaru HIGUCHI   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Transcriptomic Modification in the Cerebral Cortex following Noninvasive Brain Stimulation: RNA-Sequencing Approach

Neural Plasticity, 2016
Transcranial direct current stimulation (tDCS) has been shown to modulate neuroplasticity. Beneficial effects are observed in patients with psychiatric disorders and enhancement of brain performance in healthy individuals has been observed following tDCS.
Ben Holmes, Seung Ho Jung, Jing Lu, Jessica A. Wagner, Liudmilla Rubbi, Matteo Pellegrini, Ryan Jankord   +6 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

A mobile handshake robot system for generation of handshake request motion during active approach to a human

Nihon Kikai Gakkai ronbunshu, 2015
Humans shake hands as a sign of greeting when they first meet, to greet one another and develop a rapport. A handshake is an embodied interaction through physical contact.
Shunsuke OTA, Mitsuru JINDAI, Hitoshi YAMAUCHI, Tomio WATANABE   +3 more
doaj   +1 more source

Human-entrained embodied interaction and communication technology for human-connected IoT design

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2020
In human face-to-face conversation, embodied rhythms between speech and body motions such as nodding are mutually synchronized not only between talkers but also in a talker.
Tomio WATANABE
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source