Results 71 to 80 of about 1,891,996 (295)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Nihon Kikai Gakkai ronbunshu, 2016 Line-of-sight such as gaze and eye-contract plays an important role to enhance the embodied interaction and communication through avatars. In addition, many eyeball movement models and communication systems using avatars with the line-of-sight have been ...
Yoshihiro SEJIMA +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Nihon Kikai Gakkai ronbunshu, 2018 Along with the extreme aging of the population in Japan, the number of elderly with dementia has been increasing. Measures to address their symptoms and suppress the onset of dementia have been demanded.
Yuichi NAKAZATO +3 more
doaj +1 more source
Journal of Electrical & Electronic Systems, 2016 An industrial control user interface NrоvNdеN а flexible, extensible architecture fоr thе provision оf real-time process data tо а state-of-the-art user interface, uNNng MSHTML аN thе underlying rendering engine. Thе architecture оf thе interface NrоvNdеN а user interface thаt NN designed tо harness key industry standard ...
openaire +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Neural Plasticity, 2016 Transcranial direct current stimulation (tDCS) has been shown to modulate neuroplasticity. Beneficial effects are observed in patients with psychiatric disorders and enhancement of brain performance in healthy individuals has been observed following tDCS.
Ben Holmes +6 more
doaj +1 more source
Intelligent Human Machine Interface Design for Advanced Product Life Cycle Management Systems
, 2009 Designing and implementing an intelligent and user friendly human machine interface for any kind of software or hardware oriented application is always be a challenging task for the designers and developers because it is very difficult to understand the ...
Ahmed, Zeeshan
core +1 more source
A heuristic evaluation of the Facebook's advertising tool beacon [PDF]
, 2009 Interface usability is critical to the successful adoption of information systems. The aim of this study is to evaluate interface of Facebook's advertising tool Beacon by using privacy heuristics [4].
Cole, M, Jamal, A
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source