Human leukocyte antigen-associated drug hypersensitivity [review] [PDF]
A growing number of associations between adverse drug reactions and alleles of the human leukocyte antigen (HLA) genes are now known. Although several models have been proposed to explain these associations, an underlying molecular basis has only ...
Rossjohn, Jamie +3 more
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The human leukocyte antigen-presented ligandome of B lymphocytes [PDF]
Peptides presented by human leukocyte antigen (HLA) molecules on the cell surface play a crucial role in adaptive immunology, mediating the communication between T cells and antigen presenting cells.
Veelen, P.A. van +12 more
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Human Leukocyte Antigen (HLA) [PDF]
This book is a concise review of medically important applications of Human Leukocyte Antigen (HLA) in medicine. It covers both basic knowledge of HLA and its main clinical applications in medical practice.
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Analysis of leukocyte membrane protein interactions using protein microarrays [PDF]
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work
Foster-Cuevas, M +18 more
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The role of endogenous annexin A1 on leukocyte biology [PDF]
PhDInflammation is the body's innate immune response to the damage caused to its cells and vascularised tissue, either by injury or microbial pathogens.
Yona, Simon
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Investigation into the role of annexin 1 in the microcirculation of annexin 1 knockout mice [PDF]
PhDGlucocorticoids are used therapeutically for their anti-inflammatory and immunosuppressive actions. One of the ways they produce their potent effects is via regulation of the anti-inflammatory protein Annexin I (ANX-AI; 37 kDa protein).
Chatterjee, Bristi Emma
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The human leukocyte antigen region and colorectal cancer risk [PDF]
PURPOSE: Recently, we found a certain haplotype in the human leukocyte antigen Class III subregion to be associated with breast cancer. Epidemiologic studies have shown that breast cancer and colorectal cancer have several risk factors in common. In view
te Meerman, GJ +14 more
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Modulation of granulocyte-endothelium interactions by antileukoproteinase : inhibition of anti-type II collagen antibody-induced leukocyte attachment to the synovial endothelium [PDF]
Antileukoproteinase (ALP) is a physiological inhibitor of granulocytic serine proteases that has been shown to have anti-inflammatory properties in addition to its antiproteolytic activity.
Rikard Holmdahl +31 more
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Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation [PDF]
Expression of human leukocyte antigen (HLA)-B27 is strongly associated with predisposition toward ankylosing spondylitis (AS) and other spondyloarthropathies. However, the exact involvement of HLA-B27 in disease initiation and progression remains unclear.
Bowness, Paul +23 more
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E5 protein of human papillomavirus type 16 selectively downregulates surface HLA class I [PDF]
Papillomaviruses have evolved mechanisms that result in escape from host immune surveillance. The E5 protein is expressed early in papillomavirus infection in the deep layers of the infected epithelium.
Marchetti, Barbara +9 more
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