Results 21 to 30 of about 16,508 (72)

HLA‐Bw4 homozygosity is associated with an impaired CD4 T cell recovery after initiation of antiretroviral therapy [PDF]

open access: yes, 2008
We assessed the influence of human leukocyte antigen (HLA) alleles HLA-Bw4 and HLA-Bw6 on CD4 T cell recovery after starting successful combination antiretroviral therapy in 265 individuals. The median gains in the CD4 T cell count after 4 years were 258
Battegay, Manuel   +42 more
core   +2 more sources

Carbohydrate receptor-mediated gene transfer to human T leukaemic cells [PDF]

open access: yes, 1994
The mucin-type carbohydrate Tn cryptantigen (GalNAcα1-O-Ser/Thr, where GalNAc is N-acetyl-D-galactosamine) is expressed in many carcinomas, in haemopoietic disorders including the Tn syndrome, and on human immunodeficiency virus (HIV) coat glycoproteins,
Berger, Eric G.   +12 more
core   +1 more source

Morphologic observations of human T and B lymphocytes by scanning electron microscopy [PDF]

open access: yes, 1974
T cell concerned with cell mediated immunity and B cell concerned with humoral antibody are classified by scanning electron microscopy of the surface structure of lymphocytes using E binding lymphocytes and EAC (sensitized sheep erythrocytes treated with
Yamamoto, Isamu
core   +1 more source

Specific integrin alpha and beta chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms [PDF]

open access: yes, 2005
Integrins are adhesion receptors that are crucial to the functions of multicellular organisms. Integrin-mediated adhesion is a complex process that involves both affinity regulation and cytoskeletal coupling, but the molecular mechanisms behind this ...
Susanna C. Fagerholm   +11 more
core   +1 more source

Modulation of Toll-like receptor activity by leukocyte Ig-like receptors and their effects during bacterial infection. [PDF]

open access: yes, 2010
Toll-like receptors (TLRs) are a potent trigger for inflammatory immune responses. Without tight regulation their activation could lead to pathology, so it is imperative to extend our understanding of the regulatory mechanisms that govern TLR expression ...
Martin Vordermeier   +5 more
core   +1 more source

A common HLA-DPA1 variant is associated with hepatitis B virus infection but fails to distinguish active from inactive Caucasian carriers [PDF]

open access: yes, 2012
Background and Aims: Chronic infection with the hepatitis B virus (HBV) is a major health issue worldwide. Recently, single nucleotide polymorphisms (SNPs) within the human leukocyte antigen (HLA)-DP locus were identified to be associated with HBV ...
Stefan Zeuzem   +15 more
core   +1 more source

A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells [PDF]

open access: yes, 2007
Viral mutational escape can reduce or abrogate recognition by the T cell receptor (TCR) of virus-specific CD8+ T cells. However, very little is known about the impact of cytotoxic T lymphocyte (CTL) epitope mutations on interactions between peptide–major
Feeney, M   +56 more
core   +1 more source

In vivo imaging and quantitative analysis of leukocyte directional migration and polarization in inflamed tissue [PDF]

open access: yes, 2009
Directional migration of transmigrated leukocytes to the site of injury is a central event in the inflammatory response. Here, we present an in vivo chemotaxis assay enabling the visualization and quantitative analysis of subtype-specific directional ...
Alexander Georg Khandoga   +11 more
core   +1 more source

Human Leukocyte Antigen-DR Mismatch Is Associated With Increased In-Hospital Mortality After a Heart Transplant [PDF]

open access: yes, 2013
Objectives: Although previous studies have investigated the effect of human leukocyte antigen matching on long-term outcomes after heart transplants, its role in the prognosis after a heart transplant remains unclear, particularly with respect to ...
Abete P   +10 more
core   +1 more source

False-positive reactivity of anti-human leukocyte antigen antibodies detected using the single-antigen bead assay [PDF]

open access: yes, 2021
The single-antigen bead assay (SABA) demonstrates high sensitivity and specificity for detecting anti-human leukocyte antigen (HLA) antibodies. However, SABA may produce false-positive results for anti-HLA antibodies.
김신영   +3 more
core   +1 more source

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