Attenuation of leukocyte sequestration by selective blockade of PECAM-1 or VCAM-1 in murine endotoxemia [PDF]
, 2004 Background: Molecular mechanisms regulating leukocyte sequestration into the tissue during endotoxemia and/or sepsis are still poorly understood. This in vivo study investigates the biological role of murine PECAM-1 and VCAM-1 for leukocyte sequestration
Kuebler, Wolfgang M. +4 more
core +1 more source
Leukocyte sequestration in pulmonary microvessels and lung injury following systemic complement activation in rabbits [PDF]
, 1999 Inflammatory reactions are associated with sequestration of leukocytes in the lung. Complement activation leads to accumulation of leukocytes in alveolar septa and alveoli, to lung edema and hemorrhage.
Kuhnle, Gerhard E. H. +5 more
core +1 more source
Investigation into the role of annexin 1 in the microcirculation of annexin 1 knockout mice [PDF]
, 2005 PhDGlucocorticoids are used therapeutically for their anti-inflammatory and immunosuppressive actions. One of the ways they produce their potent effects is via regulation of the anti-inflammatory protein Annexin I (ANX-AI; 37 kDa protein).
Chatterjee, Bristi Emma
core +2 more sources
Vascular inflammation in central nervous system diseases: adhesion receptors controlling leukocyte-endothelial interactions [PDF]
, 2010 Leukocyte trafficking from the blood into the tissues represents a key process during inflammation and requires multiple steps mediated by adhesion molecules and chemoattractants. Inflammation has a detrimental role in several diseases, and in such cases,
Gabriela Constantin +9 more
core +1 more source
Unraveling the complexity of lipid body organelles in human eosinophils
, 2014 Lipid-rich organelles are common in many cell types. In cells, such as adipocytes, these organelles are termed LDs, whereas in other cells, such as leukocytes, they are called LBs.
Weller, Peter +3 more
core +1 more source
Accurate imputation of human leukocyte antigens with CookHLA [PDF]
, 2021 The recent development of imputation methods enabled the prediction of human leukocyte antigen (HLA) alleles from intergenic SNP data, allowing studies to fine-map HLA for immune phenotypes.
Jia, Xiaoming +15 more
core +1 more source
Individual variation in 3-methylbutanal: A putative link between human leukocyte antigen and skin microflora [PDF]
, 2008 The human derma emits volatile compounds whose interaction with a receiver's olfactory sensory system may affect individual recognition and mating preferences.
Goodfellow, Michael +9 more
core +1 more source
The Oxidative Folding and Misfolding of Human Leukocyte Antigen-B27
, 2011 The major histocompatibility complex class I molecule human leukocyte antigen (HLA)-B27 is strongly associated with a group of inflammatory arthritic disorders known as the spondyloarthropathies.
Guiliano, D.B. +4 more
core +1 more source
The role of endogenous annexin A1 on leukocyte biology [PDF]
, 2005 PhDInflammation is the body's innate immune response to the damage caused to its cells and vascularised tissue, either by injury or microbial pathogens.
Yona, Simon
core +2 more sources
Identification of the ancestral killer immunoglobulin-like receptor gene in primates [PDF]
, 2006 Background: Killer Immunoglobulin-like Receptors (KIR) are essential immuno- surveillance molecules. They are expressed on natural killer and T cells, and interact with human leukocyte antigens.
Penny Coggill +26 more
core +1 more source