Results 11 to 20 of about 7,851,591 (65)

Characterisation of bovine leukocyte Ig-like receptors [PDF]

, 2012
Leukocyte Immunoglobulin-like receptors (LILR) are innate immune receptors involved in regulating both innate and adaptive immune functions. LILR show more interspecies conservation than the closely related Killer Ig-like receptors, and homologues have ...
Jones, DC, Singh, M, Allen, RL, Trowsdale, J, Laing, K, Butcher, P, Bhuju, S, Hogan, L, Vordermeier, M   +8 more
core   +4 more sources

Human Leukocyte Antigen B*27-Negative Spondyloarthritis: Clinical, Serological, and Radiological Features of a Single-Center Cohort

Diagnostics, 2023
The strong genetic association between HLA-B*27 and spondyloarthritis (SpA) accounts for about 90% of the susceptibility to axial SpA (axSpA), and the presence of HLA-B*27 is helpful in classifying patients according to the Assessment of SpondyloArthritis International Society (ASAS) classification criteria. However, over the years, other HLA-B alleles
Francesco Maria Mariani, Alessia Alunno, Evy Di Ruscio, Piera Altieri, Claudio Ferri, Francesco Carubbi   +5 more
openaire   +3 more sources

Polymorphisms of human leukocyte antigen B*27 on clinical phenotype of spondyloarthritis in Chinese [PDF]

Journal of Clinical Laboratory Analysis, 2017
BackgroundIn recent years, an ever‐increasing number of alleles of human leukocyte antigen B*27 (HLA‐B*27) have been identified. This study aimed to establish an updated method for HLA‐B*27 subtyping, and to investigate the impact of HLA‐B*27 polymorphisms on the clinical phenotype of spondyloarthritis (SpA).MethodsOverall, 184 SpA patients were ...
Hai‐Jun Ma, Qing‐Feng Yin, Yun Liu, Yin Wu, Tie‐Chui Zhu, Ming‐Hao Guo   +5 more
openaire   +2 more sources

Modulation of granulocyte-endothelium interactions by antileukoproteinase : inhibition of anti-type II collagen antibody-induced leukocyte attachment to the synovial endothelium [PDF]

, 2006
Antileukoproteinase (ALP) is a physiological inhibitor of granulocytic serine proteases that has been shown to have anti-inflammatory properties in addition to its antiproteolytic activity.
Rikard Holmdahl, Kutty Nandakumar, Vollmar, Brigitte,, Sehnert, Bettina,, Harald Burkhardt, Rupert Hallmann, Hallmann, Rupert,, Anja Kühl, Reinhard Voll, Ibrahim, Saleh, Nandakumar, Kutty Selva,, Holmdahl, Rikard, Voll, Reinhard,, Burkhardt, Harald,, Gierer, Philip,, Bettina Sehnert, Burkhardt, Harald, Hallmann, Rupert, Saleh Ibrahim, Nandakumar, Kutty Selva, Vollmar, Brigitte, Ibrahim, Saleh,, Kühl, Anja,, Kuehl, Anja, Sehnert, Bettina, Philip Gierer, Gierer, Philip, Kühl, Anja, Lund University., Voll, Reinhard, Holmdahl, Rikard,, Brigitte Vollmar   +31 more
core   +1 more source

A case of human leukocyte antigen B-27-associated ocular hypotony successfully treated with golimumab

Indian Journal of Ophthalmology, 2018
A 42-year-old male presented to us after an episode of acute anterior human leukocyte antigen (HLA)-B27-associated uveitis, and intraocular pressure (IOP) in the right eye was 4 mmHg. Ultrasound biomicroscopy revealed ciliary body edema with supraciliary effusion.
Parthopratim Dutta Majumder, Ruchika Lakra, G Yamuna, Anindya Kishore Majumder, Viswanath Kaushik   +4 more
openaire   +3 more sources

Association Between Human Leukocyte Antigen-B*27 and Pathogenesis in Seronegative Spondyloarthropathies in Federation of Bosnia and Herzegovina

Archives of Rheumatology, 2019
Objectives: This study aims to investigate the low-resolution human leukocyte antigen (HLA)-B locus polymorphisms between unrelated healthy individuals and patients with diagnosis of seronegative spondyloarthropathies and determine risky and protective allelic groups and genotypes.
Elma, Fejzić, Izet, Eminović, Jasenko, Karamehić, Amela, Šahović, Sanela, Šišić, Damir, Suljević   +5 more
openaire   +3 more sources

Human Leukocyte Antigen-B*27 Allele Subtype Prevalence and Disease Association of Ankylosing Spondylitis among South Indian Population

Indian Journal of Rheumatology, 2018
Aim: Ankylosing spondylitis (AS) is a chronic inflammatory arthritis mainly affecting articular and extraarticular structures. AS clinical manifestations also involve sacroiliac joints and spine. Genetic factors play a key role in AS susceptibility. AS-associated subtypes of human leukocyte antigen (HLA)-B27 and other HLA-B alleles vary in different ...
Vikram Haridas, Praveenkumar Shetty, M Nirmal Kumar, K C Vasanthakumar, Kiran Haridas, Vitthal Khode, Anil Bargale   +6 more
openaire   +2 more sources

Leukocyte margination in alveolar capillaries: Interrelationship with functional capillary geometry and microhemodynamics [PDF]

, 1999
The pulmonary capillary microvasculature harbors a large pool of intravascularly marginated leukocytes. In this study, we investigated the interrelationship of leukocyte margination with characteristics of functional capillary geometry and ...
Kuhnle, Gerhard E. H., Kuebler, Wolfgang M., Goetz, Alwin Eduard, W.M. Kuebler, A.E. Goetz, G.E.H. Kuhnle   +5 more
core   +1 more source

ACE-inhibition prevents postischemic coronary leukocyte adhesion and leukocyte-dependent reperfusion injury [PDF]

, 1997
Objective: Polymorphonuclear leukocytes (PMN), retained in the microvascular bed, can contribute to postischemic myocardial reperfusion injury. Since a beneficial effect of ACE-inhibition on reperfusion injury has been reported, we investigated the ...
Weber, Christian, Messmer, Konrad, Habazettl, Helmut, Kupatt, Christian, Gerlach, Eckehart, Zahler, Stefan, Becker, Bernhard F., C Kupatt   +7 more
core   +1 more source

In vivo imaging and quantitative analysis of leukocyte directional migration and polarization in inflamed tissue [PDF]

, 2009
Directional migration of transmigrated leukocytes to the site of injury is a central event in the inflammatory response. Here, we present an in vivo chemotaxis assay enabling the visualization and quantitative analysis of subtype-specific directional ...
Alexander Georg Khandoga, Peter Bihari, Khandoga, Andrej, Reichel, Christoph Andreas, Rehberg, Markus, Fritz Krombach, Christoph Andreas Reichel, Markus Rehberg, Bihari, Peter, Krombach, Fritz, Khandoga, Alexander Georg, Andrej Khandoga   +11 more
core   +2 more sources