Results 121 to 130 of about 289,641 (264)

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, EarlyView.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source

Association of human leukocyte antigen B genotypes with COVID-19 severity in Egyptian patients. [PDF]

Sci Rep
Abdelmonem R, Selim H, Abdullah Mohamed S, Amponsah RD, Nabil Roshdy M, Hassan Hashish M.   +5 more
europepmc   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

Human leukocyte antigen study on a cohort of 149 Vietnamese umbilical cord blood samples. [PDF]

Tzu Chi Med J
Yang KL, Phu CD, Chen SP, Wen SH, Lin PY.   +4 more
europepmc   +1 more source

Clinical Significance of PD‐L1 and HLA Expression in Esophageal Squamous Cell Carcinoma in Response to Immunotherapy

Annals of Gastroenterological Surgery, EarlyView.
This study evaluated immune‐related biomarkers in esophageal squamous cell carcinoma treated with immune checkpoint inhibitors after postoperative recurrence. PD‐L1 expression in tumor‐associated macrophages and tumor cells, together with HLA class I downregulation and HLA‐DR expression, were associated with favorable responses to immunotherapy.
Kosuke Kanemitsu, Yoshiyuki Tagayasu, Yoshihiro Komohara, Cheng Pan, Rin Yamada, Yukio Fujiwara, Kazuto Harada, Keisuke Kosumi, Yoshifumi Baba, Masaaki Iwatsuki   +9 more
wiley   +1 more source

Recipient Human Leukocyte Antigen-DR Homozygosity and Access to Quality Kidneys. [PDF]

Kidney Int Rep
Brosi DN, Lopez R, Arrigain S, LaVanchy R, Agrawal A, Isaacson D, Tambur AR, Schold JD.   +7 more
europepmc   +1 more source

An Integrated and Robust Deep Learning Framework for Denoising and Analyzing Single‐Cell Spatial Transcriptomics

Advanced Intelligent Systems, EarlyView.
Single‐cell Spatial Transcriptomics Analysis and Denoising Engine is introduced as a unified deep learning framework that jointly performs denoising, clustering, and gene prioritization in spatial transcriptomics. By integrating linear and nonlinear representations within a dual‐channel architecture, it improves robustness and accuracy, uncovers ...
Yaxuan Cui, Yang Cui, Ruheng Wang, Xin Zeng, Zheyong Zhu, Ding Yi, Ruihua Guo, Tetsuya Sakurai, Kenta Nakai, Xiucai Ye, Leyi Wei, Yong Chen   +11 more
wiley   +1 more source

Human Leukocyte Antigen-G is enriched in presence of trypanosome in the dermis of individuals exposed to gambiense Human African Trypanosomiasis in Guinea and Côte d'Ivoire. [PDF]

PLoS Negl Trop Dis
Lagrave A, Camara A, Gineau L, Tichit M, Gnankou FB, Soumah AM, Camara M, N'Djetchi M, Kaboré JW, Camara O, Coulibaly B, Sépé B, Nanan V, Kouadio KAM, N'Dri L, Konan T, Milet J, Boiro S, Travaillé C, Crouzols A, Petiot N, Ilboudo H, Hardy D, Sadissou I, Bart JM, Camara M, Kaba D, Koffi M, Bucheton B, Jamonneau V, Courtin D, Rotureau B.   +31 more
europepmc   +1 more source

Late Cytomegalovirus Infections After Allogeneic Hematopoietic Cell Transplant

American Journal of Hematology, EarlyView.
ABSTRACT Graft versus host disease (GVHD) prophylaxis with posttransplant cyclophosphamide (ptCY) and cytomegalovirus (CMV) prophylaxis with letermovir have changed the clinical epidemiology of CMV infection. We studied the incidence, risk factors for, and outcomes of CMV infection after Day + 90 of allogeneic hematopoietic cell transplant (alloHCT ...
George L. Chen, Roland Bassett, Rohtesh S. Mehta, Betul Oran, Fareed Khawaja, Ella J. Ariza‐Heredia, Yosra Aljawai, Amanda Olson, May Daher, Portia Smallbone, Katayoun Rezvani, Partow Kebriaei, Uday Popat, Richard Champlin, Roy F. Chemaly, Elizabeth J. Shpall   +15 more
wiley   +1 more source

Human leukocyte antigen-incompatible living donor kidney transplantation after desensitization: experience from a major transplant centre in Mexico. [PDF]

Transpl Int
Reynoso de la Torre HL, Rojas-Campos E, Cerrillos-Gutiérrez JI, Evangelista-Carrillo LA, Banda-López A, Cruz-Landino M, Aguilar-Fletes LE, González-Correa LG, Alatorre-Moreno EV, Simancas-Ruiz PE, Salazar López CB, Miranda-Díaz AG, Sutto ST, Cardona Muñoz EG, Carvallo-Venegas M, Mendoza-Cabrera S, Mendoza Cerpa CA, Romo-Álvarez C, Arellano-Arteaga KJ, Andrade-Sierra J.   +19 more
europepmc   +1 more source