Designing the Next Generation of Biomaterials through Nanoengineering
Nanoengineering enables precise control over biomaterial interactions with living systems by tuning surface energy, defects, porosity, and crystallinity. This review highlights how these nanoscale design parameters drive advances in regenerative medicine, drug delivery, bioprinting, biosensing, and bioimaging, while outlining key translational ...
Ryan Davis Jr.+3 more
wiley +1 more source
Hematopoietic stem cell transplantation is the treatment of choice for many hematologic diseases, such as multiple myeloma, bone marrow aplasia and leukemia.
Danilo Santana Alessio Franceschi+5 more
doaj +1 more source
B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells. [PDF]
Dendritic cells comprise a system of highly efficient antigen-presenting cells involved in the initiation of T cell responses. Herein, we investigated the role of the CD28 pathway during alloreactive T cell proliferation induced by dendritic-Langerhans ...
Azuma, M+6 more
core
Biomimetic Cell Membrane‐Coated Scaffolds for Enhanced Tissue Regeneration
This review examines the development and use of cell membrane‐coated scaffolds in tissue engineering. Bioinspired phospholipid and glycocalyx coatings enhance anti‐fouling, anti‐thrombogenic, and selective molecular recognition properties. Native cell membrane coatings further support cell‐specific interactions, immune modulation, and reduced bacterial
Carmen Alvarez‐Lorenzo+5 more
wiley +1 more source
Differential and Temporal Immunomodulation of alpha4 Integrins on CD4+ Memory Cells by Bordetella pertussis and Bordetella parapertussis [PDF]
Pertussis, caused by Bordetella pertussis (B. pertussis), is reemerging worldwide due to vaccine inefficacy. The hallmarks of infection are extreme lymphocytosis and delayed recovery, which are partially associated with pertussis toxin.
Ravindra, Dipti
core +1 more source
Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka+5 more
wiley +1 more source
Heterogeneity Landscape of Circulating Tumor Cells in Clinical Utility
This study reports the heterogeneity spectrum of circulating tumor cells. The factors involved in the spectrum promote CTCs to overcome barriers in the metastatic cascade but impact the clinical outcome of cancer patients. In summary, the heterogeneities in association with CTCs ultimately reduce patient survival and facilitate increasing mortality of ...
Md Kowsar Alam+5 more
wiley +1 more source
Graft failure after T-cell-depleted human leukocyte antigen identical marrow transplants for leukemia: I. Analysis of risk factors and results of secondary transplants [PDF]
NA Kernan+9 more
openalex +1 more source
The graphical abstract illustrates the combined effect of PTT and PDT using metal‐organic frameworks (MOFs) in a cancer treatment model. Tumor‐bearing mice are irradiated with different laser lights, which activate the MOF nanoparticles within cancer cells. The MOFs produce reactive oxygen species through PDT, while PTT elevates the temperature to kill
Kayalvizhi Samuvel Muthiah+5 more
wiley +1 more source
A single amino acid substitution in the human histocompatibility leukocyte antigen DR3 beta chain selectively alters antigen presentation. [PDF]
Elizabeth Mellins+4 more
openalex +1 more source