Results 131 to 140 of about 359,068 (363)

PRMT1 Ablation in Endothelial Cells Causes Endothelial Dysfunction and Aggravates COPD Attributable to Dysregulated NF‐κB Signaling

Advanced Science, EarlyView.
This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran, Yideul Jeong, Suwoo Kim, Ji Eun Yeom, Jinwoo Lee, Wonhwa Lee, Gyu‐Un Bae, Jong‐Sun Kang   +7 more
wiley   +1 more source

Back to the future [PDF]

, 2005
Sin ...
Bach, Barker, Barnard, Billingham, Calne, Calne, Cordier, Dausset, Gatti, Hamburger, Lakkis, Main, Moskophidis, Murray, Przepiorka, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Thomas, Thomas E. Starzl, Webb, Zinkernagel, Zinkernagel, Zinkernagel   +32 more
core   +2 more sources

Human leukocyte antigen associations in postural tachycardia syndrome

Annals of Clinical and Translational Neurology, 2019
Associations between human leukocyte antigen (HLA) and postural orthostatic tachycardia syndrome (POTS) have not been investigated. We included patients diagnosed with POTS and showing orthostatic heart rate increases ≥ 50 during orthostatic vital sign ...
Yong‐Won Shin, Jangsup Moon, Tae‐Joon Kim, Do‐Yong Kim, Hyeyeon Chang, Jin‐Sun Jun, Soon‐Tae Lee, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Manho Kim, Sang Kun Lee, Kon Chu   +12 more
doaj   +1 more source

Using high-resolution human leukocyte antigen typing of 11,423 randomized unrelated individuals to determine allelic varieties, deduce probable human leukocyte antigen haplotypes, and observe linkage disequilibria between human leukocyte antigen-B and-C and human leukocyte antigen-DRB1 and-DQB1 alleles in the Taiwanese Chinese population

Tzu-Chi Medical Journal, 2017
Objective: We report here the human leukocyte antigen (HLA) allelic variety and haplotype composition in a cohort of the Taiwanese Chinese population and their patterns of linkage disequilibria on HLA-B: HLA-C alleles and HLA-DRB1: HLA-DQB1 alleles at a ...
Kuo-Liang Yang, Hsee-Bin Chen
doaj   +1 more source

A Study of Human Leukocyte D Locus Related Antigens in Graves' Disease [PDF]

, 1979
Nadir R. Farid, Laura Sampson, Elke P. Noel, John M. Barnard, Robert Mandeville, Bodil Larsen, William H. Marshall, Nicholas D. Carter   +7 more
openalex   +1 more source

Immune and Angiogenic Profiling of Mesenchymal Stem Cell Functions in a Subcutaneous Microenvironment for Allogeneic Islet Transplantation

Advanced Science, EarlyView.
With emphasis on a diabetic state, this study highlights the role of mesenchymal stem cells (MSCs) in enhancing vascularization and modulating immune responses within a subcutaneous platform for cell transplantation for type 1 diabetes (T1D). Comprehensive profiling of MSC‐induced angiogenic and immune responses, provides insight into the role of MSCs ...
Jocelyn Nikita Campa‐Carranza, Simone Capuani, Ashley L. Joubert, Nathanael Hernandez, Tommaso Bo, Octavio I. Sauceda‐Villanueva, Marzia Conte, Letizia Franco, Marco Farina, Gabrielle E. Rome, Yitian Xu, Junjun Zheng, Lissenya B. Argueta, Jean A. Niles, Fotis Nikolos, Corrine Ying Xuan Chua, Shu‐Hsia Chen, Joan E. Nichols, Norma S. Kenyon, Alessandro Grattoni   +19 more
wiley   +1 more source

Inhibitor of Apoptosis Proteins as Novel Targets in Inflammatory Processes [PDF]

, 2013
Objective: Inhibitor of apoptosis proteins (IAPs), such as X-linked or cellular IAP 1/2 (XIAP, cIAP1/2), are important regulators of apoptosis. IAP antagonists are currently under clinical investigation as anticancer agents.
Erhardt, Annette, Fürst, Robert, Kracht, Michael, Krombach, Fritz, Mayer, Bettina A., Rehberg, Markus, Reichel, Christoph A., Tiegs, Gisa, Vollmar, Angelika M., Wolf, Alexander, Zahler, Stefan   +10 more
core   +1 more source

Human Leukocyte Antigen Diversity: A Southern African Perspective

Journal of Immunology Research, 2015
Despite the increasingly well-documented evidence of high genetic, ethnic, and linguistic diversity amongst African populations, there is limited data on human leukocyte antigen (HLA) diversity in these populations.
Mqondisi Tshabalala, Juanita Mellet, Michael S. Pepper   +2 more
doaj   +1 more source

Studies with human leukocyte lysosomes. Evidence for antilysosome antibodies in lupus erythematosus and for the presence of lysosomal antigen in inflammatory diseases. [PDF]

, 1975
David Bell, Patricia A. Thiem, J H Vaughan, J P Leddy   +3 more
openalex   +1 more source

From Invaginating Site to Deep Lesion: Spatial Transcriptomics Unravels Ectopic Endometrial Penetration Features in Adenomyosis

Advanced Science, EarlyView.
This work utilizes spatial transcriptomics to map the transcriptional landscape of adenomyosis with obvious invagination structure from the invaginating site to deep lesions. By integrating with single‐cell RNA sequencing, this study elucidates the molecular features of invagination, invasion, and fibrosis, and finds the major participants and vital ...
Boyu Li, Jia Qi, Yumeng Cao, Yijing Long, Zhe Wei, Wang‐Sheng Wang, Shuanggang Hu, Yuan Wang, Qinling Zhu, Xiao Hu, Zhe Sun, Jie Zhu, Taiyang Ye, Yejie Yao, Yiwen Meng, Xuejiao Bian, Xinyi Dong, Hengyu Guan, Yunfei Huang, Yun Sun   +19 more
wiley   +1 more source