Results 171 to 180 of about 401,671 (363)

Sequence Conservation in Potential Regulatory Regions of the Mouse and Human Leukocyte Common Antigen Gene

, 1989
Nancy Johnson, Claudia Meyer, Jeanette T. Pingel, M L Thomas   +3 more
openalex   +1 more source

Expression of the human leukocyte adhesion molecule, LAM1. Identity with the TQ1 and Leu-8 differentiation antigens. [PDF]

, 1990
Thomas F. Tedder, A C Penta, H. B. Levine, Arnold S. Freedman   +3 more
openalex   +1 more source

Targeting eRNA‐Producing Super‐Enhancers Regulates TNFα Expression and Mitigates Chronic Inflammation in Mice and Patient‐Derived Immune Cells

Advanced Science, EarlyView.
Targeting eRNAs from TNFα‐associated super‐enhancers with ASOs effectively reduces TNFα expression and inflammatory responses in both mouse models and patient‐derived immune cells. The conserved nature of these regulatory regions between species highlights the potential of eRNA‐targeted approaches as a therapeutic strategy for chronic inflammatory ...
Minjeong Cho, Su Min Kim, Jiyeon Lee, Oh Chan Kwon, Wonjin Woo, Eunji Lee, Hyo Jin Park, Yeongun Lee, So Hee Dho, Tae‐Kyung Kim, Min‐Chan Park, Richard A. Flavell, Lark Kyun Kim   +12 more
wiley   +1 more source

HU LY-M3—A HUMAN LEUKOCYTE ANTIGEN

, 1983
Hilary Vaughan, Christopher H. Thompson, ROSEMARY L. SPARRO, Ian F. C. McKenzie   +3 more
openalex   +1 more source

Costimulation of T cell receptor/CD3-mediated activation of resting human CD4+ T cells by leukocyte function-associated antigen-1 ligand intercellular cell adhesion molecule-1 involves prolonged inositol phospholipid hydrolysis and sustained increase of intracellular Ca2+ levels. [PDF]

, 1992
G A van Seventer, Ezio Bonvini, Hiroshi Yamada, Antonio Conti, S Stringfellow, Carl H. June, Sunil K. Shaw   +6 more
openalex   +1 more source

BLOC1S1 Attenuates B. Melitensis 16M LPS‐Triggered Autophagy by Spatial Confinement of TDP‐43

Advanced Science, EarlyView.
This study explores how B. melitensis 16M LPS and BLOC1S1 regulate autophagy in goat spermatogonial stem cells. The 16M LPS is activating AMPK‐dependent autophagy, increasing LC3B‐II/I ratios and lysosomal genes, while Escherichia coli LPS shows no effect.
Shicheng Wan, Miao Han, Mengfei Zhang, Wenbo Chen, Fangde Xie, Xuan Luo, Wenping Wu, Congliang Wang, Donghui Yang, Bin Han, Haijing Zhu, Haisheng Yu, Na Li, Jinlian Hua   +13 more
wiley   +1 more source

Restoring NK Cell Cytotoxicity Post‐Cryopreservation via Synthetic Cells

Advanced Science, EarlyView.
In this study, it is shown that 1‐day co‐culture with activated T cells or IL‐2‐presenting synthetic cells significantly enhances NK cell motility and cytotoxicity in 2D and 3D. Notably, synthetic cells restore the impaired cytotoxic function of cryopreserved NK and CAR‐NK cells in 3D.
Xiangda Zhou, Sijia Zhang, Wenjuan Yang, Susanne Gonder, Zeinab Sadjadi, Nils Piernitzki, Alina Moter, Shulagna Sharma, Anne Largeot, Nadja Küchler, Lea Kaschek, Gertrud Schäfer, Eva C. Schwarz, Hermann Eichler, Evelyn Ullrich, Heiko Rieger, Oskar Staufer, Jérôme Paggetti, Etienne Moussay, Markus Hoth, Bin Qu   +20 more
wiley   +1 more source

Analysis of the role of leukocyte function-associated antigen-1 in activation of human influenza virus-specific T cell clones. [PDF]

, 1990
K C Kuijpers, Taco W. Kuijpers, W.P. Zeijlemaker, C.J. Lucas, René A. W. van Lier, Frank Miedema   +5 more
openalex   +1 more source

HLA-G+3027 polymorphism is associated with tumor relapse in pediatric Hodgkin's lymphoma [PDF]

, 2017
Bianchi, Maurizio, Buffardi, Salvatore, Burnelli, Roberta, Caggiari, Laura, Carosella, Edgardo D., D'Amore, Emanuele Stefano, DE ZORZI, Mariangela, Elia, Caterina, Famengo, Barbara, Farruggia, Piero, Martina, Lia, Mascarin, Maurizio, Muggeo, Paola, Mussolin, Lara, Pillon, Marta, Re, Valli, Sala, Alessandra, Santoro, Nicola, Vinti, Luciana   +18 more
core   +1 more source

Variations in Innate Immune Cell Subtypes Correlate with Epigenetic Clocks, Inflammaging and Health Outcomes

Advanced Science, EarlyView.
This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo, Josephine A. Robertson, Andrea Aparicio, Kirsten Seale, Qingwen Chen, Anne Richmond, Zhaozhen Du, Mahnoor Sulaiman, Shijie C Zheng, Esteban Ballestar, Charlotte AM Cecil, Bastiaan T Heijmans, Steve Horvath, Varun B. Dwaraka, Jessica Lasky‐Su, Ryan Smith, Riccardo E. Marioni, Andrew E Teschendorff   +17 more
wiley   +1 more source