Results 171 to 180 of about 409,119 (362)

Identification of the sequence required for expression of the 2H4 epitope on the human leukocyte common antigens. [PDF]

, 1987
Michel Streuli, Tomohiko Matsuyama, Chikao Morimoto, Stuart F. Schlossman, Hirohisa Saito   +4 more
openalex   +1 more source

Red Blood Cell‐Derived Exosomal miR‐93‐5p Promotes Lung Cancer Progression through PTEN Suppression

Advanced Science, EarlyView.
Red blood cell (RBC)‐derived exosomal miR‐93‐5p is elevated in lung cancer patients and correlates with poor outcomes. Exosomal miR‐93‐5p suppresses PTEN in cancer cells, enhancing proliferation, migration, and invasion. In mouse models, therapeutic inhibition with ASO‐miR‐93 5p reduces tumor growth, highlighting a bidirectional tumor‐RBC‐tumor axis ...
Ning Li, Pushpa Dhilipkannah, Van K Holden, Ashutosh Sachdeva, Feng Jiang   +4 more
wiley   +1 more source

Prediction of KIR3DL1 and human leukocyte antigen binding. [PDF]

J Biol Chem
Maiers M, Louzoun Y, Pymm P, Vivian JP, Rossjohn J, Brooks AG, Saunders PM.   +6 more
europepmc   +1 more source

Presence or absence of a known diabetic ketoacidosis precipitant defines distinct syndromes of “A-β+” ketosis-prone diabetes based on long-term β-cell function, human leukocyte antigen class II alleles, and sex predilection

, 2010
Ramaswami Nalini, Kerem Özer, Mario Maldonado, Sanjeet Patel, Christiane S. Hampe, Anu Guthikonda, Jesus A. Villanueva, E. O’Brian Smith, Lakshmi K. Gaur, Ashok Balasubramanyam   +9 more
openalex   +2 more sources

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

Advanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu, Yating Wang, Siming Jiang, Yi Li, Guanglan Li, Yuchu Liu, Siyuan Li, Yiming Zhou, Qinghua Liu, Yi Zhou, Wei Chen, Hongyu Li, Haiping Mao   +12 more
wiley   +1 more source

Assessment of Donor-Specific Human Leukocyte Antigen Antibodies Following Pediatric Liver Transplantation: Predictors, Protectors, and Clinical Relevance. [PDF]

Clin Transplant
Kanaan E, Ohlsson S, Kathemann S, Prusinskas B, Tsaka S, Heinemann FM, Heinold A, Schulze M, Pape L, Lainka E.   +9 more
europepmc   +1 more source

CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence [PDF]

, 2008
Emma J. Petrie, Craig S. Clements, Jie Lin, Lucy C. Sullivan, Darryl N. Johnson, Trevor Huyton, A. Héroux, Hilary L. Hoare, Travis Beddoe, Hugh H. Reid, Matthew C. J. Wilce, Andrëw G. Brööks, Jamie Rossjohn   +12 more
openalex   +1 more source

Bimetallic Peroxide Nanocomposites‐Driven Redox Dyshomeostasis to Activate Sequential Cuproptosis and Pyroptosis for Amplified Tumor Immunotherapy

Advanced Science, EarlyView.
Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He, Haixia Zhu, Peipei Kang, Lili Feng, Chenghao Yu, Yanlin Zhu, Bin Liu, Zhengxiao Guo, Piaoping Yang   +8 more
wiley   +1 more source

Murine cytomegalovirus genomic material in marrow cells; relation to altered leukocyte counts during sublethal infection of mice [PDF]

, 1987
Bale, J. F., Giller, R., Koszinowski, Ulrich H., O'Neil, M. E., Perlman, S.   +4 more
core   +1 more source

A machine learning-based method to optimize the immunogenicity of human leukocyte antigen class I-restricted neoantigens. [PDF]

Brief Bioinform
Zhang J, Zhou W, Yu J, Yan C, Liu J.
europepmc   +1 more source