Human Leukocyte Antigen alleles as an aid to STR in complex forensic DNA samples [PDF]
, 2020 Gray, Alexander +2 more
core +2 more sources
An Engineered Soluble Single‐Chain TCR Engager for KRAS‐G12V Specific Tumor Immunotherapy
Advanced Science, EarlyView.This study develops a dimeric T cell receptor engager protein specific for tumor KRAS‐G12V mutation. The engager proteins are capable of mediating the formation of synapse between T cell and tumor cell and demonstrate substantial tumor suppression efficacy.
Keke Ma +14 more
wiley +1 more source
Transcription analysis, physical mapping, and molecular characterization of a nonclassical human leukocyte antigen class I gene. [PDF]
, 1990 Michael J. Chorney +5 more
openalex +1 more source
Mapping the tumour human leukocyte antigen (HLA) ligandome by mass spectrometry
Immunology, 2018 L. Freudenmann, A. Marcu, S. Stevanović
semanticscholar +1 more source
Advanced Science, EarlyView.A phosphorothioate‐modified aptamer PTf‐SRiApt capable of disrupting “undruggable” transcription factor SCAF4‐POLR2A interaction with high inhibitory activity and biological stability is presented here. Through this inhibition, PTf‐SRiApt successfully arrested cell cycle progression, induced cell death, and elevated immune recruitment in SCAF4‐POLR2A ...
Liyan Fei +13 more
wiley +1 more source
Human leukocyte antigen F (HLA-F). An expressed HLA gene composed of a class I coding sequence linked to a novel transcribed repetitive element. [PDF]
, 1990 Dan Geraghty +3 more
openalex +1 more source
3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene Signatures
Advanced Science, EarlyView.This study developed a 3D brain vascular niche model that capture the key features of glioblastoma including perivascular infiltration, gene signature, dormancy and chemo resistance, by comparing 3D model with in vivo condition using identical glioma stem cells.
Vivian K. Lee +10 more
wiley +1 more source
Selected antibodies to leukocyte common antigen (CD45) inhibit human neutrophil chemotaxis. [PDF]
, 1991 Liana Harvath +4 more
openalex +1 more source
Advanced Microfluidics for Single Cell‐Based Cancer Research
Advanced Science, EarlyView.Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro +10 more
wiley +1 more source