Results 181 to 190 of about 409,119 (362)

Single antigen flow beads for identification of human leukocyte antigen antibody specificities in hypersensitized patients with chronic renal failure [PDF]

, 2016
Mustafa Soyöz, Tülay Kılıçaslan-Ayna, Aslı Özkızılcık-Koçyigit, Derya Güleç, İbrahim Pirim   +4 more
openalex   +1 more source

Efferocytosis‐Driven Polyamine Metabolism in Macrophages Enhances Cancer Stem Cell Enrichment after Chemotherapy in Ovarian Cancer

Advanced Science, EarlyView.
Chemotherapy‐induced efferocytosis drives ovarian cancer stem cell enrichment. By engulfing apoptotic cancer cells, macrophages upregulate ODC1 and produce putrescine, which elevates osteopontin (OPN) expression. Secreted OPN then activates the CD44 receptor on cancer cells, promoting stemness and chemoresistance.
Wenhan Li, Feiquan Ying, Xinkai Pang, Qiulei Wu, Guoqing Li, Lin Huang, Jiayu Xin, Xiaoli Liu, Pan Liu, Xiaohan Xu, Shuran Tan, Yumei Gao, Tong Liu, Si Sun, Xiaoman Wang, Yiping Wen, Liqiong Cai, Shi Du, Yuan Zhang, Jing Cai   +19 more
wiley   +1 more source

The Impact of Killer Cell Immunoglobulin-Like Receptors and Human Leukocyte Antigen-E, Human Leukocyte Antigen-G Polymorphisms on Innate Immunity and COVID-19 Severity. [PDF]

J Immunol Res
Kekik C, Temurhan S, Ogret Y, Zanjani BN, Kıvanc D, Savran Oguz F, Kose M, Oktelik FB, Deniz G.   +8 more
europepmc   +1 more source

Human leukocyte antigen in Japanese patients with idiopathic inflammatory myopathy

, 2019
Hiroshi Furukawa, Shomi Oka, Aya Kawasaki, Misaki Hidaka, Kota Shimada, Yuya Kondo, Atsushi Ihata, Takashi Matsushita, Takumi Matsumoto, Atsushi Hashimoto, Isao Matsumoto, Akiko Komiya, Kouji Kobayashi, Atsumu Osada, Masao Katayama, Akira Okamoto, Keigo Setoguchi, Hajime Kono, Yasuhito Hamaguchi, Toshihiro Matsui, Naoshi Fukui, Hiroaki Tamura, Kazuhiko Takehara, Shouhei Nagaoka, Shoji Sugii, Takayuki Sumida, Naoyuki Tsuchiya, Shigeto Tohma   +27 more
openalex   +2 more sources

A Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines

Advanced Science, EarlyView.
OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.
Qimeng Yin, Chenchen Zhang, Jiahao Li, Kun Huang, Min Qiu   +4 more
wiley   +1 more source

Association of Human Leukocyte Antigen Polymorphisms With Moderate-to-Severe Dry Eye With and Without Sjögren's Syndrome. [PDF]

Invest Ophthalmol Vis Sci
Chen Z, Jiang D, Zheng Q, Xing S, Li J, Lin L, Ren L, Xu H, Yu X, Tong L, Chen W.   +10 more
europepmc   +1 more source

SP770OUTCOMES OF MYCOPHENOLATE MONOTHERAPY FOR HUMAN LEUKOCYTE ANTIGEN (HLA)-IDENTICAL SIBLING LIVING KIDNEY TRANSPLANTATION [PDF]

, 2018
Ahmed Elkeraie, Rowan Zyada
openalex   +1 more source

Bimetallic Nanozyme Amplifier for Synergistic Ferroptosis‐Cuproptosis and Metabolic Reprogramming to Reshape Immunosuppressive Tumor Microenvironment

Advanced Science, EarlyView.
The Bimetallic Nanozyme Amplifier (PEG@AuCZ@CC) to maximize hydrogen peroxide production and reprogram tumor metabolism from glycolysis to oxidative phosphorylation. This shift enhances ferroptotic/cuproptotic signaling cascades and creates a glucose‐enriched but lactate‐depleted tumor microenvironment (TME), effectively overcoming immune tolerance in ...
Jianzhang Luo, Kunzhao Huang, Xiaoyuan Yi, Pei Lu, Huaying Xie, Wen Li, Qingyu Zeng, Feifei He, Duo Wang, Liyan Wang   +9 more
wiley   +1 more source

Prediction of immunogenicity of Rh antigens using in silico analysis of binding to human leukocyte antigen peptide, Basic/Translational Research. [PDF]

PLoS One
Youk HJ, Cho YJ, Han YH, Kim SW, Ko DH.
europepmc   +1 more source

Puerarin Targets MIC19 to Suppress Mitochondrial Metabolism of Tumor‐Infiltrating Tregs and Enhance Anti‐tumor Immunity

Advanced Science, EarlyView.
Puerarin targets mitochondrial MIC19 in tumor‐infiltrating Tregs, impairing their immunosuppressive function and enhancing antitumor immunity. This study uncovers the metabolic dependency of tumor‐infiltrating Tregs and highlights a potential metabolic‐targeted immunotherapeutic strategy for liver cancer. Abstract Regulatory T cells (Tregs) are pivotal
Yu Li, Ziyan Song, Jianjun Ding, Yiheng Zhou, Tianning Huang, Qufei Qian, Miao Yu, Wenzhao Chen, Jiazheng Liu, Ling Lu, Qiuyang Chen   +10 more
wiley   +1 more source