Results 181 to 190 of about 658,106 (408)

A Study of Human Leukocyte D Locus Related Antigens in Graves' Disease [PDF]

, 1979
Nadir R. Farid, Laura Sampson, Elke P. Noel, John M. Barnard, Robert Mandeville, Bodil Larsen, William H. Marshall, Nicholas D. Carter   +7 more
openalex   +1 more source

Human Leukocyte Antigen DQ2.2 and Celiac Disease

Journal of Pediatric Gastroenterology and Nutrition - JPGN, 2013
Patients with celiac disease (CD) lacking both human leukocyte antigen (HLA)-DQ2.5 in cis (DQA1*05:01, DQB1*02:01) or trans (DQA1*05:05, DQB1*02:02) configuration and HLA-DQ8 (DQA1*03:01, DQB1*03:02) are considered to be rare. Therefore, absence of these
A. Mubarak, E. Spierings, V. Wolters, I. V. van Hoogstraten, C. Kneepkens, R. Houwen   +5 more
semanticscholar   +1 more source

Computer-assisted vaccine design [PDF]

arXiv, 2009
We define a new parameter to quantify the antigenic distance between two H3N2 influenza strains: we use this parameter to measure antigenic distance between circulating H3N2 strains and the closest vaccine component of the influenza vaccine. For the data between 1971 and 2004, the measure of antigenic distance correlates better with efficacy in humans ...
arxiv  

Inhibition of Aberrant Activated Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis by Leishmania Peptide via the Regulation of Fatty Acid Synthesis Metabolism

Advanced Science, EarlyView.
LACK156‐173 is internalized into RA‐FLSs via CAPN2‐mediated endocytosis and inhibits the aggressive phenotype of RA‐FLSs by restoring dysregulated fatty acid synthesis metabolism mediated by overexpressed FASN. The findings suggest that targeting the restoration of fatty acid metabolism could potentially alleviate synovial invasion and joint damage in ...
Jianling Su, Xuemei Fan, Yaoyao Zou, Guangtao Fu, Shiqi Feng, Xiaoxue Wang, Yongmei Yu, Lin Li, Zhenhua Bian, Rongrong Huang, Linmang Qin, Jiping Chen, Qin Zeng, Kai Yan, Caiyue Gao, Zhexiong Lian, Xin Li, Yang Li   +17 more
wiley   +1 more source

Studies with human leukocyte lysosomes. Evidence for antilysosome antibodies in lupus erythematosus and for the presence of lysosomal antigen in inflammatory diseases. [PDF]

, 1975
David Bell, Patricia A. Thiem, J H Vaughan, J P Leddy   +3 more
openalex   +1 more source

Cloned mouse cells with natural killer function and cloned suppressor T cells express ultrastructural and biochemical features not shared by cloned inducer T cells. [PDF]

, 1983
We have examined the morphology, cytochemistry, and biochemistry of mouse leukocyte subsets by analyzing cloned leukocyte populations specialized to perform different immunologic functions.
Cantor, H, der Simonian, H, Dvorak, AM, Dvorak, HF, Galli, SJ, Goldin, J, Marcum, JA, Monahan, RA, Nabel, G, Pyne, K, Rosenberg, RD   +10 more
core  

Inhibitor of Apoptosis Proteins as Novel Targets in Inflammatory Processes [PDF]

, 2013
Objective: Inhibitor of apoptosis proteins (IAPs), such as X-linked or cellular IAP 1/2 (XIAP, cIAP1/2), are important regulators of apoptosis. IAP antagonists are currently under clinical investigation as anticancer agents.
Erhardt, Annette, Fürst, Robert, Kracht, Michael, Krombach, Fritz, Mayer, Bettina A., Rehberg, Markus, Reichel, Christoph A., Tiegs, Gisa, Vollmar, Angelika M., Wolf, Alexander, Zahler, Stefan   +10 more
core   +1 more source

The Effect of Proteasome Inhibition on the Generation of the Human Leukocyte Antigen (HLA) Peptidome*

Molecular & Cellular Proteomics, 2013
The Major histocompatibility complex (MHC) class I peptidome is thought to be generated mostly through proteasomal degradation of cellular proteins, a notion that is based on the alterations in presentation of selected peptides following proteasome ...
E. Milner, Lilach Gutter-Kapon, Michal Bassani-Strenberg, Eilon Barnea, Ilan Beer, A. Admon   +5 more
semanticscholar   +1 more source

Advances in Nano‐Immunomodulatory Systems for the Treatment of Acute Kidney Injury

Advanced Science, EarlyView.
Based on the biodegradability and the immunological reactiveness, IMNs can be broadly classified into four categories. The first category includes types of biologically derived materials that cause immunomodulatory action and biodegradability like nanoparticles of cell membranes, extracellular vesicles, and exosomes.
Chenli Zhang, Zeli Xiang, Pengfei Yang, Ling Zhang, Jun Deng, Xiaohui Liao   +5 more
wiley   +1 more source

A single amino acid substitution in the human histocompatibility leukocyte antigen DR3 beta chain selectively alters antigen presentation. [PDF]

, 1988
Elizabeth Mellins, B Arp, Barbara Ochs, M Kellis, Donald Pious   +4 more
openalex   +1 more source