Results 41 to 50 of about 595,560 (387)

High-throughput and Sensitive Immunopeptidomics Platform Reveals Profound Interferonγ-Mediated Remodeling of the Human Leukocyte Antigen (HLA) Ligandome

open access: yesMolecular & Cellular Proteomics, 2017
Comprehensive knowledge of the human leukocyte antigen (HLA) class-I and class-II peptides presented to T-cells is crucial for designing innovative therapeutics against cancer and other diseases.
Chloé Chong   +8 more
semanticscholar   +1 more source

Evaluation of ascitic soluble human leukocyte antigen-G for distinguishing malignant ascites from benign ascites

open access: yesTumor Biology, 2017
The overexpression of soluble human leukocyte antigen-G is associated with malignant tumours. The purpose of our study was to detect soluble human leukocyte antigen-G concentrations in ascites and to evaluate the value of ascitic soluble human leukocyte ...
Juan Sun, Yan-Xiang Chang, Chun-Yan Niu
doaj   +1 more source

Regulatory immune cells in transplantation [PDF]

open access: yes, 2012
Immune regulation is fundamental to any immune response to ensure that it is appropriate for the perceived threat to the host. Following cell and organ transplantation, it is essential to control the innate immune response triggered by the injured ...
Bushell, Andrew   +2 more
core   +1 more source

Two probable human leukocyte antigen haplotypes in association with human leukocyte antigen HLA-DRB1*13:50:01 identified in 41 randomized unrelated Taiwanese individuals

open access: yesTzu Chi Medical Journal, 2021
Objectives: Here, we show two probable haplotypes associated with the human leukocyte antigen (HLA) DRB1*13:50:01 allele. The haplotypes were observed from 41 randomized unrelated Taiwanese individuals among a population of 23,064 individuals tested ...
Nondumiso Ayanda Mazibuko   +1 more
doaj   +1 more source

Kidney Transplantation: The Challenge of Human Leukocyte Antigen and Its Therapeutic Strategies

open access: yesJournal of Immunological Research, 2018
Kidney transplantation remains the treatment of choice for end-stage renal failure. When the immune system of the recipient recognizes the transplanted kidney as a foreign object, graft rejection occurs.
T. Alelign   +5 more
semanticscholar   +1 more source

HLA Class I (A and B) Allele Polymorphism in a Moroccan Population Infected with Hepatitis C Virus

open access: yesCurrent Issues in Molecular Biology
Hepatitis C virus (HCV) infection is one of the major health burdens worldwide. Its course depends on the virus itself and the host’s immune responses.
Safa Machraoui   +6 more
doaj   +1 more source

Establishing a Causal Link between Ankylosing Spondylitis and Inflammatory Bowel Disease: A Review of the Literature

open access: yesInternational Journal of Medical Students, 2016
The link between ankylosing spondylitis and inflammatory bowel disease is unclear, however it is hypothesized that there is a causal link between the inheritance of a human leukocyte antigen B27 allele and the development of inflammatory bowel disease ...
Jaclyn Rivington, Michael Gillett
doaj   +1 more source

‘Hotspots’ of Antigen Presentation Revealed by Human Leukocyte Antigen Ligandomics for Neoantigen Prioritization

open access: yesFrontiers in Immunology, 2017
The remarkable clinical efficacy of the immune checkpoint blockade therapies has motivated researchers to discover immunogenic epitopes and exploit them for personalized vaccines. Human leukocyte antigen (HLA)-binding peptides derived from processing and
Markus Müller   +3 more
semanticscholar   +1 more source

A Case of Diamond Blackfan Anemia with Mutation in Ribosomal Protein S19 [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Diamond Blackfan Anemia (DBA) is a rare disorder which presents with anemia in early infancy. This disorder is genetically and clinically heterogeneous in nature. The inheritance is mainly autosomal dominant.
John Solomon   +5 more
doaj   +1 more source

Spondyloarthritis and the Human Leukocyte Antigen (HLA)-B*27 Connection

open access: yesFrontiers in Immunology, 2021
Heritability of Spondyloarthritis (SpA) is highlighted by several familial studies and a high association with the presence of human leukocyte antigen (HLA)-B*27.
Chengappa G. Kavadichanda   +4 more
doaj   +1 more source

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