Results 71 to 80 of about 595,560 (387)

Human leukocyte antigen-A*33:03-B*58:01-DRB1*15:140, a deduced probable human leukocyte antigen haplotype in association with a human leukocyte antigen low-incidence allele DRB1*15:140 in Taiwanese individuals: A case analysis

open access: yesTzu Chi Medical Journal, 2019
Objective: Human leukocyte antigen (HLA)-DRB1*15:140 is a low-frequency allele in the HLA-DRB1 locus. The aim of this study is to confirm the ethnicity of DRB1*15:140 and to deduce a probable HLA-DRB1*15:140-associated HLA haplotype in Taiwanese ...
Kuo-Liang Yang, Zheng-Zhong Zheng
doaj   +1 more source

Sarcopenia and Variation in the Human Leukocyte Antigen Complex [PDF]

open access: yesThe Journals of Gerontology: Series A, 2019
Abstract Background Aging is characterized by chronic inflammation plus loss of muscle mass and strength, termed sarcopenia. Human leukocyte antigen (HLA) types are drivers of autoimmune disease, although with limited penetrance.
David Melzer   +6 more
openaire   +4 more sources

The multiple faces of leukocyte interstitial migration

open access: yes, 2014
Spatiotemporal control of leukocyte dynamics within tissues is critical for successful innate and adaptive immune responses. Homeostatic trafficking and coordinated infiltration into and within sites of inflammation and infection rely on signaling in ...
Germain, R., Lämmermann, T.
core   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Platelet antibody detection by flow cytometry: an effective method to evaluate and give transfusional support in platelet refractoriness

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2013
BACKGROUND: Immune platelet refractoriness is mainly caused by human leukocyte antigen antibodies (80-90% of cases) and, to a lesser extent, by human platelet antigen antibodies.
Carolina Bonet Bub   +5 more
doaj   +1 more source

Association between human leukocyte antigen and COVID-19 severity

open access: yesActa Medica Iranica, 2021
In the last days of 2019, a new coronavirus emerged in Wuhan, China, and less than 3 months its disease now called COVID-19 was announced a global pandemic by WHO.
Reza Hajebi   +7 more
doaj   +1 more source

Detection of CD33 expression on monocyte surface is influenced by phagocytosis and temperature [PDF]

open access: yes, 2019
CD33 is a myeloid-associated marker and belongs to the sialic acid-binding immunoglobulin (Ig)-like lectin (Siglec) family. Such types of receptors are highly expressed in acute myeloid leukemia, which could be used in its treatment.
Baisaeng, Nuttakorn   +7 more
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Allele and haplotype frequencies of human platelet and leukocyte antigens in platelet donors

open access: yesEinstein (São Paulo)
Objective To described the allele and haplotype frequencies of human leukocyte antigen genes at the -A, -B loci and human platelet antigen genes for human platelet antigen systems 1 to 9, 11 and 15 in blood.
Valeria de Freitas Dutra   +6 more
doaj   +1 more source

Determination of an unrelated donor pool size for human leukocyte antigen-matched platelets in Brazil

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2016
Background: Successful transfusion of platelet refractory patients is a challenge. Many potential donors are needed to sustain human leukocyte antigen matched-platelet transfusion programs because of the different types of antigens and the constant needs
Carolina Bonet Bub   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy