Results 11 to 20 of about 111,709 (254)

Human Leukocyte Antigens in Pregnancy and Preeclampsia [PDF]

open access: yesFrontiers in Genetics, 2022
Preeclampsia is a pregnancy-induced hypertensive disorder, the pathophysiology of which includes underlying maternal cardiovascular disease, deficient spiral artery remodeling during placenta development, and inflammatory immune responses at the maternal-
Omonigho Aisagbonhi, Gerald P. Morris
doaj   +6 more sources

Associations between human leukocyte antigens and renal function [PDF]

open access: yesScientific Reports, 2021
Human leukocyte antigens (HLA) have been associated with renal function, but previous studies report contradictory findings with little consensus on the exact nature or impact of this observation.
Marcus Lowe   +8 more
doaj   +2 more sources

Accurate imputation of human leukocyte antigens with CookHLA [PDF]

open access: yesNature Communications, 2021
Human leukocyte antigen (HLA) genes influence many immune phenotypes, however methods to impute HLA type have been limited in accuracy. Here, the authors present an HLA imputation method, CookHLA, which uses locally embedded prediction markers to ...
Seungho Cook   +7 more
doaj   +2 more sources

Human leukocyte antigens are associated with salivary level of active MMP‐8 [PDF]

open access: yesClinical and Experimental Dental Research, 2021
Objectives This case control study examined the associations of HLA antigens and periodontitis with the salivary level of active MMP‐8 (aMMP‐8). Materials and Methods A total of 202 subjects, registered as Swiss bone marrow donors, participated in the ...
Matti Mauramo   +5 more
doaj   +2 more sources

Imputing amino acid polymorphisms in human leukocyte antigens. [PDF]

open access: yesPLoS ONE, 2013
DNA sequence variation within human leukocyte antigen (HLA) genes mediate susceptibility to a wide range of human diseases. The complex genetic structure of the major histocompatibility complex (MHC) makes it difficult, however, to collect genotyping ...
Xiaoming Jia   +7 more
doaj   +2 more sources

Psoriasis and Psoriatic Arthritis—Associated Genes, Cytokines, and Human Leukocyte Antigens [PDF]

open access: yesMedicina
In recent years, research has intensified in exploring the genetic basis of psoriasis (PsO) and psoriatic arthritis (PsA). Genome-wide association studies (GWASs), including tools like ImmunoChip, have significantly deepened our understanding of disease ...
Marek Zalesak   +2 more
doaj   +2 more sources

Neonatal Bell’s Palsy and Possible Correlation with Human Leukocyte Antigens [PDF]

open access: yesOman Medical Journal, 2019
The authors discussed the different etiologies contributing to the development of BP, namely congenital, inflammatory, traumatic, infectious, syndromic, and ischemic factors.
Mahmood Dhahir
doaj   +2 more sources

Large-scale statistical mapping of T-cell receptor β sequences to human leukocyte antigens [PDF]

open access: yesFrontiers in Immunology
IntroductionT-cell receptors (TCRs) interacting with peptides presented by human leukocyte antigens (HLAs) are the foundation of the adaptive immune system, but population-level analysis of TCR–HLA interactions is lacking.MethodsWe statistically ...
H. Jabran Zahid   +13 more
doaj   +2 more sources

Association of human leukocyte antigens Class I and Class II antigens with chronic periodontitis in East India [PDF]

open access: yesJournal of Indian Society of Periodontology, 2017
Context: Human leukocyte antigens (HLAs) have an important role in the determination of susceptibility and resistance to periodontal diseases in humans, which may vary from population to population.
Mona Chowdhury   +3 more
doaj   +2 more sources

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