Results 211 to 220 of about 111,709 (254)
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Human leukocyte antigen in hydatidiform mole
International Journal of Gynecology & Obstetrics, 1993AbstractOBJECTIVE: To find any possible association between human leukocyte antigen (HLA) as a genetic marker and the development of hydatidiform mole (HM). METHOD: The lymphocyte microtoxicity technique was used to study the HLA antigens in 3 groups: 18 women with hydatidiform mole and their husbands (study group), 300 normal women (first control ...
A R, Souka +4 more
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Human leukocyte antigens and drug hypersensitivity
Current Opinion in Allergy & Clinical Immunology, 2007The present article reviews the recent literature on the identification of human leukocyte antigen (HLA) alleles as major susceptible genes for drug hypersensitivity and discusses the clinical implications.Several recent studies have reported strong genetic associations between HLA alleles and susceptibility to drug hypersensitivity.
Wen-Hung, Chung +2 more
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Human Leukocyte Antigens in Bell's Palsy
Annals of Otology, Rhinology and Laryngology, 1988Ninety-three patients with Bell's palsy including 12 members of two families with familial Bell's palsy were typed for human leukocyte antigens (HLAs). Significant association between HLAs and Bell's palsy was found. The association of certain HLAs with the palsy may predict the specific clinical course and prognosis.
T Shibahara, Naoaki Yanagihara
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Human leukocyte antigen epitope antigenicity and immunogenicity
Current Opinion in Organ Transplantation, 2014Human leukocyte antigen (HLA) antibodies are now recognized as being specific for epitopes which can be defined structurally with amino acid differences between HLA alleles. This article addresses two general perspectives of HLA epitopes namely antigenicity, that is their reactivity with antibody and immunogenicity, that is their ability of eliciting ...
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Human leukocyte antigens and Gaucher disease
Blood Cells, Molecules, and Diseases, 2013Gaucher disease (GD) is caused by the reduced activity of lysosomal enzyme glucocerebrosidase, which leads to the accumulation of glucocerebroside in macrophages and a chronic stimulation of the immune system. GD is divided into 3 main types according to the presence or absence of neurological involvement and to its presentation (acute or chronic ...
Filippo, Vairo +8 more
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Human leukocyte antigen-DP in leukemia
Cancer, 1988Human leukocyte antigen-DP (HLA-DP) typing was performed on patients with chronic myelogenous leukemia (CML, n = 44), acute nonlymphoblastic leukemia (ANLL, n = 34), or acute lymphoblastic leukemia (ALL, n = 41). Frequencies of DPw alleles in CML and ANLL patients were not significantly different from 254 controls, except that in ANNL DPw1 was absent ...
G, Pawelec +5 more
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Surface Antigens of Human Leukocytes
1991Publisher Summary The aim of this chapter is to provide a comprehensive overview of the well-characterized surface molecules of human leukocytes. It is useful to have a brief compilation of this field as a whole that would enable one to quickly find at least the basic information on both the well-known and less familiar molecules and provide a ...
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Human Leukocyte Antigens in Undifferentiated Spondyloarthritis
Seminars in Arthritis and Rheumatism, 2007Undifferentiated spondyloarthritis (USpA) is a major member of the spondyloarthritis family. Ankylosing spondylitis (AS), the prototype of the family, is a largely genetic disease, with human leukocyte antigens (HLA)-B27 being the essential gene. Other genes in the HLA region have also been implicated.
Hsien-Tzung, Liao +7 more
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Characterization of human leukocyte differentiation antigens
Immunology Today, 1987What would impel 190 different laboratories to work together in the performance of more than 150 000 assays to characterize about 800 antibodies? Participants in the 3rd International Workshop on Human Leukocyte Differentiation Antigens generally shared the conviction that such cooperative effort has the potential to bring order out of the chaos of ...
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The human leukocyte antigens and their relationship to infection
The American Journal of Surgery, 1993Human leukocyte antigen DR (HLA-DR) expression on peripheral blood monocytes has been found to correlate highly with infection in many clinical scenarios. This is particularly true for the trauma patient, where changes in HLA-DR expression predate and therefore often predict development of infection.
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