Results 131 to 140 of about 8,915,710 (312)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Vaccine and vaccination as a part of human life: In view of COVID-19. [PDF]
Biotechnol J, 2022 K B M, Nayar SA, P V M.
europepmc +1 more source
Human Capital Inequality, Life Expectancy and Economic Growth [PDF]
This paper presents a model in which inequality affects per capita income when individuals decide to invest in education taking into account their life expectancy, which depends to a large extent on the human capital of their parents.
Amparo Castello-Climent, Rafael Domenech
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The Buddhist outlook on life and political life in Hanoi nowadays
Studia HumanitatisBased on the Buddhist outlook on life, the author analyses the relationship between religion and politics and clarifies the Buddhism influence on the political life of Hanoi in two periods: the Ly-Tran dynasties and the present. The shared point of these
Tran Thi Hanh
doaj
Journal of NeuroinflammationAging is a major risk factor for neurodegeneration. However, the mechanisms by which age-related disruptions in brain homeostasis induce neurodegeneration remain controversial.
Fuka Sato +13 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
HUMOR IN JALAN PINGGIR CRITICISM COLUMN IN SILATURAHIM RUBRIC SUARA MUHAMMADIYAH MAGAZINE (A PRAGMATIC STUDY) [PDF]
, 2011 In human life, human beings will not be separated from problems, any time man strives to get trough the problem, ranging from minor problems in life, to the tragedy that changed someone’s life, this thesis tells about a character named Andrew Laeddis is ...
HANDAYANI, NITA DIAN
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source