Results 141 to 150 of about 2,920,388 (265)
Comparative Analysis of Mammal Genomes Unveils Key Genomic Variability for Human Life Span. [PDF]
Farré X +9 more
europepmc +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Bacterial low-abundant taxa are key determinants of a healthy airway metagenome in the early years of human life. [PDF]
Pust MM, Tümmler B.
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Pushing the boundaries of MEG based on optically pumped magnetometers towards early human life. [PDF]
Corvilain P +8 more
europepmc +1 more source
Correction to: Comparative Analysis of Mammal Genomes Unveils Key Genomic Variability for Human Life Span. [PDF]
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An Identification Method for Road Hypnosis Based on the Fusion of Human Life Parameters. [PDF]
Wang B +6 more
europepmc +1 more source

