Results 161 to 170 of about 22,575,443 (355)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
The origins and functional effects of postzygotic mutations throughout the human life span. [PDF]
Science, 2023 Rockweiler NB +14 more
europepmc +1 more source
Life-Cyle Fertility Behavior and Human Capital Accumulation [PDF]
This paper develops and implements a semiparametric estimator for investigating, with panel data, the importance of human capital accumulation, non-separable preferences of females and child care costs on females life-cycle fertility and labor supply ...
George-Levi Gayle, Robert Miller
core
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
The human life vs economic loss dilemma: Relation between death rate and the output rate in Europe during the Covid 19 pandemic. [PDF]
J Policy Model, 2023 Bollino CA.
europepmc +1 more source
The Sacredness of Human Life In a Desacralized World [PDF]
, 1999 DeMarco, Donald
core +2 more sources
Human Capital Inequality, Life Expectancy and Economic Growth [PDF]
This paper provides a theoretical model in which inequality affects per capita income when individuals decide to accumulate human capital depending on their life expectancy.
Climent, Amparo Castello +1 more
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Editorial: Presence and Daily Exposure to Endocrine Disruptors: How Can Human Life Change? [PDF]
Front Endocrinol (Lausanne), 2021 Grasselli E, Dvorakova M, Graceli JB.
europepmc +1 more source