Results 41 to 50 of about 10,130,146 (289)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
, 2022 Human-Machine Connection is a 25-minute looped visual narrative presented across 315 extremely thin vertical screens (approx. 3cm x 300cm), spread over 7 stories.
Ward, Alistair +2 more
core +1 more source
Journal of Electrical & Electronic Systems, 2016 An industrial control user interface NrоvNdеN а flexible, extensible architecture fоr thе provision оf real-time process data tо а state-of-the-art user interface, uNNng MSHTML аN thе underlying rendering engine. Thе architecture оf thе interface NrоvNdеN а user interface thаt NN designed tо harness key industry standard ...
openaire +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Hazards Associated with Human Machine Interface in Part 121 Operations Based on ASRS Reports
International Journal of Aviation, Aeronautics, and Aerospace, 2019 Hazard identification is the first step of safety risk management within a safety management system. Hazards of human-machine interaction could exist within Part 121 operations, of which the operator is unaware.
Brian T Musselman
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Development of Unified Interface for Multi-Vendors’ CNC Based on Machine State Model [PDF]
한국정밀공학회지, 2018 The Human Machine Interface (HMI) is dependent on the Computerized Numerical Control (CNC). As a result, the HMI software is developed according to the interface method of each CNC in duplicate.
Joo Sung Yoon +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source