Results 41 to 50 of about 3,474,590 (264)

Human pluripotent stem cells in contemporary medicine

open access: yesИсследования и практика в медицине, 2015
Human pluripotent stem cells (hPSCs) are capable of indefinite proliferation and can be differentiated into any cell type of the human body. Therefore, they are a promising source of cells for treatment of numerous degenerative diseases and injuries ...
S. A. Rodin
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

“DO YOU SUPPOSE THEY WANT GM BABIES?” [PDF]

open access: yesS&F_scienzaefilosofia.it, 2018
“DO YOU SUPPOSE THEY WANT GM BABIES?” New techniques for editing genes could transform biological research, with almost unlimited potential, says a new report from the UK Nuffield Council on Bioethics.1 But the advent of a cheap, precise, and ...
Fuschetto, Cristian
doaj  

Unprecedented reorganization of development history of traditional medicine: Part I

open access: yesTraditional Medicine and Modern Medicine, 2020
According to the period development and the typical characteristics of medical stages, traditional medicine can be divided into six aspects: legendary traditional medicine, instinctive traditional medicine, witchcraft traditional medicine, empirical ...
Wenxian Liu, Jingjing Le, Jingcheng Dong
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Human Fetal Progenitor Tenocytes for Regenerative Medicine

open access: yesCell Transplantation, 2016
Tendon injuries are very frequent and affect a wide and heterogeneous population. Unfortunately, the healing process is long with outcomes that are not often satisfactory due to fibrotic tissue appearance, which leads to scar and adhesion development ...
A. Grognuz   +4 more
doaj   +1 more source

Human biological rhythm in traditional Chinese medicine

open access: yesJournal of Traditional Chinese Medical Sciences, 2016
Traditional Chinese medicine (TCM) has a comprehensive and thorough understanding of biological rhythm. Biological rhythm is an inherent connotation of “harmony between human and nature”, one of the thoughts in TCM.
Tianxing Zhang   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Antiviral Efficacy of the Traditional Chinese Medicine Mixture Yuanzhixingrenheji Against Human Adenovirus-7 In Vitro, In Vivo, and in a Clinical Retrospective Study

open access: yesPathogens
Human adenovirus type 7 (HAdV-7) is a significant pathogen responsible for viral community-acquired pneumonia in children. To date, no specific antiviral agents have been approved for clinical use against HAdV infections.
Qiuchi Lv   +8 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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