Results 221 to 230 of about 2,261,504 (355)

Artificial intelligence and computational methods in human metabolism research: A comprehensive survey. [PDF]

J Pharm Anal
Zhang M, Wan Y, Wang J, Li S, Li H.
europepmc   +1 more source

An atlas of human metabolism. [PDF]

Sci Signal, 2020
Robinson JL, Kocabaş P, Wang H, Cholley PE, Cook D, Nilsson A, Anton M, Ferreira R, Domenzain I, Billa V, Limeta A, Hedin A, Gustafsson J, Kerkhoven EJ, Svensson LT, Palsson BO, Mardinoglu A, Hansson L, Uhlén M, Nielsen J.   +19 more
europepmc   +1 more source

In Vitro Metabolism of Isopropylated and tert-Butylated Triarylphosphate Esters Using Human Liver Subcellular Fractions

, 2020
Allison L. Phillips, Nicholas J. Herkert, Jake C. Ulrich, Jessica H. Hartman, Matthew T. Ruis, Ellen M. Cooper, P. Lee Ferguson, Heather M. Stapleton   +7 more
openalex   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Bioavailability, Human Metabolism, and Dietary Interventions of Glucosinolates and Isothiocyanates: Critical Insights and Future Perspectives. [PDF]

Foods
Narra F, Galgani G, Harris CB, Moreno DA, Núñez-Gómez V.   +4 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Essential Trace Elements in the Human Metabolism. [PDF]

Biology (Basel)
da Silva JAL.
europepmc   +1 more source

Ether Link Cleavage Is the Major Pathway of Iodothyronine Metabolism in the Phagocytosing Human Leukocyte and also Occurs In Vivo in the Rat [PDF]

, 1983
Albert Burger, Dennis Engler, Ulrich Buergi, M Weissel, G Steiger, Sidney H. Ingbar, Richard E. Rosin, Bernard Babior   +7 more
openalex   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

MXene/Carboxymethyl Chitosan Moisture Responsive Soft Actuator with Diode-Like Actuation for Versatile Applications Driven by Human Metabolism. [PDF]

Adv Sci (Weinh)
Xu L, Ling Y, Li Z, Xu X, Li X, Chang L, Peng Q, Hu Y.   +7 more
europepmc   +1 more source