Results 161 to 170 of about 45,224 (267)

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao   +11 more
wiley   +1 more source

Milk and dairy product composition

open access: yes, 2013
The first section of this chapter provides detailed information on the composition of animal milks used for human consumption, including milk from both major dairy species (cow, buffalo, goat and sheep) and minor species (yak, mithun, musk ox, mare ...
Wijesinha-Bettoni, R, Burlingame BA
core  

Connecting Grazing, Forage, and Milk Metabolomes to Enhance Consumer Health

open access: yes
The objective of this work was to explore the effect of taxonomically and phytochemically rich swards, as opposed to ‘status quo’ monoculture of ryegrass and white clover swards, on animals and milk, by assessing the metabolomic profile of plant and milk
Philip Wescombe   +2 more
core   +1 more source

Study on Food Antigens Transferred into Breast Milk

open access: yes, 2007
74検体の母乳中に移行した食物抗原(オボムコイド、オボアルブミン、β一ラクトグロブリン、カゼイン及びグリアジン)をELISA法にて分析した。その結果、母乳中に各食物抗原は、11-34%の頻度、12.8-44.3ng/m1の最大濃度で存在していた。母乳中に移行した食物抗原の濃度は母乳のIgA濃度と正相関が認められ、5種類の食物抗原特異的IgAが全ての母乳に存在していた。これらの結果より、母乳中に移行した食物抗原はIgAと免疫複合体を形成していることが推測された。また ...
Isomura, Haruhiko, Totani, Masayuki
core  

A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation

open access: yesAdvanced Science, EarlyView.
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu   +7 more
wiley   +1 more source

Lactoferrin is responsible for the fungistatic effect of human milk

open access: yes, 2000
Human milk has recognized anti-microbial effects and it has been repeatedly shown that breast-fed infants have fewer and less severe infections than formula-fed infants. While most studies have focused on anti-bacterial and anti-viral activities few have
Lagerqvist, Carina,   +3 more
core  

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

open access: yesAdvanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng   +14 more
wiley   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

open access: yesAdvanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi   +23 more
wiley   +1 more source

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