Results 51 to 60 of about 1,243,598 (300)

Establishing a novel community-focussed lactation support service: a descriptive case series

International Breastfeeding Journal, 2022
Background Although breastfeeding is widely acknowledged as protecting both infant and maternal health postnatally, a partial or complete shortfall of maternal milk can occur for a range of reasons.
Samantha Griffin, Jo Watt, Sophie Wedekind, Solange Bramer, Yasmin Hazemi-Jebelli, Robert Boyle, Gillian Weaver, Natalie S. Shenker   +7 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Enhanced versus standard fortification of pasteurized donor human milk for growth in very low birth weight infants: a randomized controlled trial

Frontiers in Nutrition
IntroductionVery-low-birthweight (VLBW) infants on pasteurized donor human milk (PDHM) have poorer growth compared to infants on fortified mother's milk, suggesting that standard fortification methods for PDHM are inadequate.MethodsWe designed a ...
Chengsi Ong, Anng Anng Wong, Siew Tin Wong, Ying Zheng, Cynthia Pui Chan Pang, Cynthia Pui Chan Pang, Pooja Agarwal Jayagobi, Pooja Agarwal Jayagobi, Joo Guan Yeo, Joo Guan Yeo, Joo Guan Yeo, Kee Thai Yeo, Kee Thai Yeo, Mei Chien Chua, Mei Chien Chua, Mei Chien Chua   +15 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Receiving screened donor human milk as part of a community‐based lactation support programme reduces parental symptoms of anxiety and depression

Maternal and Child Nutrition
Infant feeding decisions and maternal mental health are closely tied. Donor human milk (DHM) protects premature infant health and development and can reduce hospital stays.
Amy Brown, Sam Griffin, Gillian Weaver, Natalie Shenker   +3 more
doaj   +1 more source

Bovine milk with variant β-casein types on immunological mediated intestinal changes and gut health of mice

Frontiers in Nutrition, 2022
Dietary proteins provide bioactive peptides, which are important for host gastrointestinal functions. We hypothesized that A2-type β-casein could provide gastrointestinal benefits and improve the immune and gut health.
Bin Liu, Bin Liu, Weicang Qiao, Weicang Qiao, Minghui Zhang, Minghui Zhang, Yanpin Liu, Yanpin Liu, Junying Zhao, Junying Zhao, Lijun Chen, Lijun Chen   +11 more
doaj   +1 more source

Paroxetine in human milk [PDF]

British Journal of Clinical Pharmacology, 1999
Aims  The primary aims of the study were to estimate the exposure of infants to paroxetine via breast milk and to determine the maternal milk:plasma ratio (M/P) of paroxetine. Secondary aims were to compare single point and area under the curve (AUC) estimates of M/P, to assess variability of M/P in fore and hind milk, and to ...
E J, Begg, S B, Duffull, D A, Saunders, R C, Buttimore, K F, Ilett, L P, Hackett, P, Yapp, D A, Wilson   +7 more
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Influence of Milk Thistle Shot on Quality Parameters of the Sour-milk Beverage [PDF]

, 2018
Modern complicated ecological conditions cause a general necessity in improving the food structure of the population due to improving the quality, biological value and taste characteristics of products.
Bilyk, O. (Oksana), Gutyj, B. (Bogdan), Hachak, Y. (Yuriy), Nagovska, V. (Volodimyra), Slyvka, N. (Natalya)   +4 more
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source