Results 71 to 80 of about 8,229,738 (277)

Targeting Hippocampal PTEN Suppresses Ferroptosis and Rescues Cognitive Decline in Alzheimer's Disease via Dual AKT/GSK3β/Nrf2 and AKT/STAT3 Axes

open access: yesAdvanced Science, EarlyView.
PTEN knockdown activates AKT phosphorylation, promoting Nrf2 nuclear translocation and STAT3 activation, which upregulates GPX4 and antioxidant enzymes HO‐1, SOD1, SOD2, and NQO1. These coordinated changes reduce lipid peroxidation and ROS, inhibit ferroptosis, and ultimately ameliorate cognitive impairment in APP/PS1 transgenic mice, highlighting a ...
Da‐Wei Wang   +5 more
wiley   +1 more source

Articulation between nursing systems and operational procedures: nursing perspectives of milk banks

open access: yesRevista de Enfermagem da Universidade Federal de Santa Maria, 2017
Aim: to understand the articulation facets of Nursing Care Systematization with the regulations used by nurses of the Human Milk Bank. Method: a descriptive study of a qualitative approach, carried out from May to November2014, inthe seven milk banks of ...
Giovanna Rosario Soanno Marchiori   +5 more
doaj   +1 more source

Banking on Milk [PDF]

open access: yes, 2019
Banking on Milk takes the reader on a journey through the everyday life of donor human milk banking across the United Kingdom (UK) and beyond, asking questions such as the following: Why do people decide to donate? How do parents of recipients hear about human milk? How does milk donation impact on lifestyle choices?
Tanya Cassidy   +2 more
openaire   +2 more sources

Composition and Variation of Macronutrients, Immune Proteins, and Human Milk Oligosaccharides in Human Milk From Nonprofit and Commercial Milk Banks

open access: yes, 2017
Background:When human milk is unavailable, banked milk is recommended for feeding premature infants. Milk banks use processes to eliminate pathogens; however, variability among methods exists.Research aim:The aim of this study was to compare the ...
Carlito B. Lebrilla   +5 more
core   +1 more source

Metabolic Reprogramming in Glioblastoma Stem Cells Promotes Radiation Resistance Through a H3K18la/USP30/MBOAT2 Axis

open access: yesAdvanced Science, EarlyView.
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao   +13 more
wiley   +1 more source

Recomendaciones para la creación y el funcionamiento de los bancos de leche materna en España

open access: yesAnales de Pediatría, 2018
Resumen: La mejor alimentación para un recién nacido es la leche de su propia madre. En aquellos casos en los que esta no está disponible, especialmente en los recién nacidos muy prematuros o de muy bajo peso al nacer, así como en otros recién nacidos ...
Javier Calvo   +8 more
doaj   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

"انسانی دودھ کی خرید وفروخت اور رضاعت کے مسائل Buying and Selling of Human Milk and Foster Relationships "

open access: yesالإيضاح, 2017
"This paper discusses the Islamic jurisprudence as well as the scientific stance regarding breast feeding. Breast feeding is a natural gift for a new born baby, which not only nourishes the infant but also provides great immunity to him.
Khair Muhammad Asif Memon
doaj  

Recommendations for the creation and operation of maternal milk banks in Spain

open access: yesAnales de Pediatría (English Edition), 2018
It is widely agreed that the best source of nutrition for the newborn is the milk of their own mothers. In those cases where it is not available, especially in very premature and/or very low birth weight infants, as well as other sick newborns, the ...
Javier Calvo   +8 more
doaj   +1 more source

Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu   +10 more
wiley   +1 more source

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