Results 81 to 90 of about 154,657 (284)
Advanced Science, EarlyView.ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li +8 more
wiley +1 more source
The effect of formal credit on output and employment in rural India [PDF]
This paper estimates the output, investment, employment and wage effect of institutional credit using district-level panel data from India. Using a two-stage model to distinguish demand for formal credit from supply, the authors conclude that increased ...
Binswanger, Hans P. +1 more
core
Advanced Science, EarlyView.This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin +14 more
wiley +1 more source
Advanced Science, EarlyView.This work identifies M1 macrophage‐mediated inflammation as a key driver of BMSC senescence and bone microstructural deterioration at the enthesis. A tissue‐adhesive hydrogel delivering senomorphic small extracellular vesicles suppresses this inflammatory‐senescent cascade and enhances BMSC resilience by inhibiting the cGAS‐STING‐NF‐κB pathway.
Lingzhi Kong +8 more
wiley +1 more source
Brazilian network of human milk banks: a network based on trust
RECIIS, 2018 This article bases on a study that aimed to identify the existing links in the rBLH-BR – Rede Brasileira de Bancos de Leite Humano (Brazilian Network of Human Milk Banks).
Mariana Simoes Barros +2 more
doaj
Exploring trends of macronutrients in Danish human donor milk
Clinical Nutrition Open ScienceSummary: Donor milk obtained from milk banks is a source of infant nutrition for mothers that cannot produce their own milk. Milk banks quality control the milk when donated, testing for the presence of pathogenic bacteria, protein and fat concentrations
Lea Holritz +4 more
doaj +1 more source
Advanced Science, EarlyView.The cover image shows that vascular endothelial cells play an important role in lung metastasis of TNBC. Endothelial Sohlh2 acts as a gatekeeper against TNBC lung metastasis by limiting endothelial activation and tumor cell passage. PRMT5 reduces Sohlh2 stability, weakening this protective barrier.
Ruihong Zhang +8 more
wiley +1 more source
Comparative analyses of holder pasteurization vs. HTST pasteurization for donor milk: a cost-minimization study applicable to human milk banks. [PDF]
Int Breastfeed J, 2023 Escuder Vieco D +5 more
europepmc +1 more source
Advanced Science, EarlyView.Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li +13 more
wiley +1 more source
Representations of women milk donors on donations for the human milk bank
Cadernos de Saúde Coletiva, 2016 Human milk banks (HMBs) have difficulty maintaining and increasing their stocks, and the number of women enrolling as members remains low. The present qualitative study, based on social representation theory, aimed to understand women’s representations ...
Wanessa Debôrtoli de Miranda +3 more
doaj +1 more source