Results 91 to 100 of about 8,216,754 (227)

Effects of Prebiotics on Antioxidant Activity of Goat Milk Fermented by Lactobacillus plantarum L60

open access: yes, 2017
The production of functional fermented goat milk with synbiotic have attracted widespread attention recently with the purpose of promoting health.
Guowei Shu   +4 more
core   +2 more sources

Infants Are Exposed to Human Milk Oligosaccharides Already in utero

open access: yesFrontiers in Pediatrics, 2018
Human milk oligosaccharides (HMOs) are complex carbohydrates that are highly abundant in and, in their complexity, unique to human milk. Accumulating evidence indicates that exposure to HMOs in the postnatal period affects immediate as well as long-term ...
Audra Wise   +10 more
doaj   +1 more source

Maternal Prebiotic Supplementation Modifies Associations Between Intrapartum Antibiotics and Infant Allergy

open access: yesAllergy, EarlyView.
This study examined whether antibiotic use altered the risk of infant allergic disease within a maternal prebiotics supplementation trial. Intrapartum antibiotics were maternal antibiotics administered during childbirth, from the onset of labour or induction until 1‐h before delivery.
Summer V. M. Walker   +10 more
wiley   +1 more source

Human Milk Oligosaccharides in the Prevention of Necrotizing Enterocolitis: A Journey From in vitro and in vivo Models to Mother-Infant Cohort Studies

open access: yesFrontiers in Pediatrics, 2018
Preterm infants who receive human milk instead of formula are 6- to 10-times less likely to develop necrotizing enterocolitis (NEC), one of the most common and devastating intestinal disorders that affects 5–10% of all very-low-birth-weight infants ...
Lars Bode
doaj   +1 more source

Historical Aspects of Human Milk Oligosaccharides [PDF]

open access: yesAdvances in Nutrition, 2012
This review focuses on important observations regarding infant health around 1900 when breastfeeding was not considered a matter of importance. The discovery of lactobacilli and bifidobacteria and their relevance for health and disease was an important milestone leading to a decrease in infant mortality in the first year of life.
openaire   +2 more sources

The Origins of Allergy: An Outside‐In, Bioenergetic Hypothesis

open access: yesAllergy, EarlyView.
ABSTRACT Allergic disease has risen too rapidly for inherited susceptibility to explain it, and the risk variants so far reported lie in the epithelial barrier and in type‐2 immunity. We propose a five‐layer model in which epithelial barrier and bioenergetic dysfunction may precede and promote type‐2 immune deviation rather than arise solely as its ...
Peter K. Smith   +9 more
wiley   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

open access: yesBritish Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė   +5 more
wiley   +1 more source

Extracellular vesicles in pharmacology: Innovations in drug delivery and therapeutic applications in cancer

open access: yesBritish Journal of Pharmacology, EarlyView.
Extracellular vesicles (EVs) are a diverse population of membrane nanoparticles secreted by nearly all cell types, playing a key role in intercellular communication by transferring bioactive macromolecular cargo. In cancer, EVs shape both the local tumour microenvironment and distant premetastatic niches.
Evangelia Pantazaka   +3 more
wiley   +1 more source

Milk‐Derived Signals Guide Neonatal Hematopoiesis and Respiratory Defense

open access: yesImmunology &Cell Biology, EarlyView.
This commentary summarises a recent paper in Cell by Howard et al. showing that osteopontin shapes the infant microbiome, which in turn directs early immune development in the airways. This early programming confers protection against respiratory tract infections that persists well beyond infancy.
Jonatan Leffler   +2 more
wiley   +1 more source

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