Results 101 to 110 of about 3,598,736 (304)
Monitoring Human Exposure to 2-Hydroxyethylating Carcinogens
Environmental Health Perspectives, 1996 It is known that human hemoglobin contains low levels of N-terminal N-(2-hydroxyethyl)valine. Possible sources of this modified amino acid are exposure to ethylene oxide or other 2-hydroxy-ethylating agents. Although such processes are likely to occur endogenously, the exogenous contribution to the adduct formation is unclear.
Farmer, Peter B. +2 more
openaire +3 more sources
Street-level surveillance: human agency and the electronic monitoring of offenders [PDF]
, 2007 Recent years have witnessed an increase in new ‘technologies of control’ that decrease reliance upon labour intensive forms of policing. The electronic monitoring of offenders represents just one section of the expanding industry in ‘techno-corrections’
Paterson, Craig
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Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Baltic Journal of Law & Politics, 2013 The article explores the dynamics of the Georgian and South Ossetian conflict which has been violent over the last twenty years. It reached a critical peak again in 2008 resulting in new security developments and post-conflict situation which drifts away
Jasutis Gražvydas
doaj +1 more source
Targeted monitoring for human pharmaceuticals in vulnerable source and final waters [PDF]
, 2012 A range of pharmaceuticals has been detected in soils, surface waters and groundwaters across the world. While the reported concentrations are generally low (i.e. sub μg l-1 in surface waters), the substances have been observed throughout the year across
Bersuder, Phillipe +6 more
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Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Frontiers in Aging NeuroscienceEarly-stage Alzheimer's disease (AD) remains difficult to assess using conventional linguistic or cognitive assessments, which often overlook subtle and individualized disruptions in speech.
Kevin Mekulu, Faisal Aqlan, Hui Yang
doaj +1 more source
South African Journal of Childhood Education, 2019 Background: Many South African children attend African language medium of instruction (MOI) schools, learn English as an additional language and switch to English MOI three years later.
Maxine Schaefer, Janeli Kotzé
doaj +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source