Results 131 to 140 of about 8,048,182 (359)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

The Compositional Nature of Verb and Argument Representations in the Human Brain [PDF]

open access: yes, 2013
How does the human brain represent simple compositions of objects, actors,and actions? We had subjects view action sequence videos during neuroimaging (fMRI) sessions and identified lexical descriptions of those videos by decoding (SVM) the brain ...
Barbu, Andrei   +12 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Pandemics, conservation, and human-nature relations. [PDF]

open access: yesClim Chang Ecol, 2021
Gebara MF, May PH, Platais G.
europepmc   +1 more source

Personification in Environmental Advertising [PDF]

open access: yes, 2012
The article investigates how the personification communicates the human-nature relationship in the environmental ...
Гудзь, Н. О.
core  

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Human-nature connectedness as a pathway to sustainability: A global meta-analysis. [PDF]

open access: yesConserv Lett, 2022
Barragan-Jason G   +4 more
europepmc   +1 more source

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