Results 41 to 50 of about 14,023,849 (296)

The “Okusuri Charm” movement in Japan: Prescription drug accessories emerging on X (Twitter)

open access: yesJournal of General and Family Medicine
Background In this digital age, social networks may offer an avenue for individuals to obtain drugs illicitly beyond the prescribed amount. Users on X (Twitter)® have ingeniously fabricated fashionable accessories that employ prescription drug sheets ...
Tatsuki Ikejiri   +4 more
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

Release of marketed individuals increases the risk of genetic disturbance in the pet insect Trypoxylus dichotomus [PDF]

open access: yesNeoBiota
Genetic disturbance can be caused by the release or escape of individuals with different genetic characteristics into wild habitats, risking impacts on native biodiversity.
Tomo Hamano   +8 more
doaj   +3 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A trial of structured debate as a self‐learning method for students and young healthcare providers to discuss social issues in general and family medicine: A case report in Japan

open access: yesJournal of General and Family Medicine
The structured debate as a means of medical education for medical students and young healthcare providers was performed, with diverse topics related to general and family medicine.
Tatsuki Ikejiri   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Network-cycle motif participation is associated with individual and collective wealth in Honduran villages

open access: yesScientific Reports
Geodesic cycles, or loops of nodes connected in a sequence within a network, are an important if under-studied network motif, and their prominence or deficiency is associated with both beneficial and detrimental properties in diverse kinds of networks ...
Shivkumar Vishnempet Shridhar   +4 more
doaj   +1 more source

Assessing the Use of Artificial Hibernacula by the Great Crested Newt (Triturus cristatus) and Smooth Newt (Lissotriton vulgaris) in Cold Climate in Southeast Norway

open access: yesDiversity, 2018
Construction of artificial overwintering habitats, hibernacula, or newt hotels, is an important mitigation measure for newt populations in urban and agricultural areas.
Børre K. Dervo   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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