Results 51 to 60 of about 8,092,812 (313)

A Developmental Systems Account of Human Nature [PDF]

open access: yes, 2018
It is now widely accepted that a scientifically credible conception of human nature must reject the folkbiological idea of a fixed, inner essence that makes us human.
Griffiths, Paul Edmund, Stotz, Karola
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Early Cretaceous troodontine troodontid (Dinosauria: Theropoda) from the Ohyamashimo Formation of Japan reveals the early evolution of Troodontinae

open access: yesScientific Reports
A new troodontid dinosaur, Hypnovenator matsubaraetoheorum gen. et sp. nov., is described based on an articulated postcranial skeleton recovered from the fluvial deposits of the Albian Ohyamashimo Formation of the Sasayama Group in Tambasasayama City ...
Katsuhiro Kubota   +2 more
doaj   +1 more source

Dostoevsky - Strakhov - Tolstoy: Toward to the Story of One Conflict

open access: yesRUDN Journal of Philosophy, 2021
The well-known epistolary conflict between Fyodor Dostoevsky and Nikolai Strakhov over the latter's slander of the great Russian writer's terrible sins is considered in the article from the point of view a philosophical anthropology and relations not two
Svetlana M. Klimova
doaj   +1 more source

HUMAN NATURE OR HUMANITY: BETWEEN GENES AND VALUES [PDF]

open access: yes, 2012
We are within nature and culture, conditioned simultaneously by genes and meanings. This form of our self-understanding is the result of fundamental modifications that happened in modern philosophical anthropology and of the impact of the natural Science.
Tuchańska, Barbara
core  

Nature versus built [PDF]

open access: yes, 2020
Nature is made up of various living and non-living things which is related to plants, animals and other features such as mountains, deserts and seas. They are connected and some of the relationships between members are direct and obvious and ecosystem ...
Jais, Noor Maisara   +1 more
core  

Tabula Rasa and Human Nature [PDF]

open access: yes, 2012
It is widely believed that the philosophical concept of 'tabula rasa' originates with Locke's Essay Concerning Human Understanding and refers to a state in which a child is as formless as a blank slate.
Agamben   +54 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Needs-Based Partial Theory of Human Injustice: Oppression, Dehumanization, Exploitation, and Systematic Inequality in Opportunities to Address Human Needs [PDF]

open access: yes, 2019
The article presents an original needs-based partial theory of human injustice and shows its relationship to existing theories of human need and human liberation.
Dover, Michael Alan
core   +3 more sources

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