Results 71 to 80 of about 8,092,812 (313)

Fear, anxiety, and boredom [PDF]

, 2020
Phenomenology's central insight is that affectivity is not an inconsequential or contingent characteristic of human existence. Emotions, moods, sentiments, and feelings are not accidents of human existence. They do not happen to happen to us.
Elpidorou, Andreas, Freeman, Lauren
core   +1 more source

Anarchist-Socialist Praxis and Embodied Human Nature

Eidos. A Journal for Philosophy of Culture
The idea of human nature can be wielded to justify exploitation and domination, but drawing on the work of Noam Chomsky, Murray Bookchin and others, I argue consideration of our embodied nature can help humans thrive.
James Anderson
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Human Nature in Ancient Philosophy and its Influence On Modern Philosophy

Kalagatos
The concept of "human nature" is analyzed from the perspective of classical philosophy, with a focus on the thought of Mencius, a great Confucian philosopher.
Nguyen Thi Thu, Nguyen Van Thanh, Nguyen Minh Hoan   +2 more
doaj   +1 more source

The rethinking and enhancement of the natural and cultural heritage of the cultural landscapes: the case of Sečovlje and Janubio saltpans [PDF]

, 2019
Cultural landscapes represent a complex category where the nature-culture dichotomy seem to not be able to unfold the main features and the profound relations that humans have with the environment.
Abad Espinoza, Luis Gregorio
core   +6 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Solidarity and human nature

Serviço Social em Revista, 2010
The concept of solidarity inhabits the collective unconscious and is usually related to something consensual, linked to the most basic values of mankind, but to expand that understanding leads to more complex views.
Luis Miguel dos Santos Luzio, Bernardo Carlos Spaulonci Chiachia Matos de Oliveira   +1 more
doaj   +1 more source

30 days wild: development and evaluation of a large-scale nature engagement campaign to improve well-being [PDF]

, 2016
There is a need to increase people’s engagement with and connection to nature, both for human well-being and the conservation of nature itself. In order to suggest ways for people to engage with nature and create a wider social context to normalise ...
A Wilhelm-Rechmann, A Zuo, AC Prévot-Julliard, AD Barnosky, Adam Cormack, AF Hayes, AM Abdel-Khalek, B Cugelman, BB Lin, C Maller, CA Capaldi, Christopher M. Somers, CM Bruni, CM Frantz, CM Pollard, CP Bonell, D Haluza, DC Des Jarlais, EK Nisbet, EK Nisbet, EK Nisbet, EK Nisbet, F Mayer, J Chapman, J Chapman, J Ernst, J McCambridge, J Vining, JM Ostrove, JP Habicht, JS Johnson-Pynn, K-P Tam, L Newman, L Rychetnik, Lucy McRobert, M Richardson, M Richardson, Miles Richardson, P Schultz, P. Stevens, PW Schultz, R Cervinka, R Kaplan, R Russell, Ralph Underhill, RM Baron, RM Pyle, RR Dunn, RW Sanson-Fisher, SR Kellert, T Hartig, T Taylor, W Cronon, Z Skandrani   +53 more
core   +4 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Modeling roles and trade-offs in multiplex networks

Nature Communications
Multiplex social networks capture multiple types of relations among the same people. Their structure reflects how exchanges arise from individual attributes related to independence, the status or resources of others related to dependence, and mutual ...
Nikolaos Nakis, Sune Lehmann, Nicholas A. Christakis, Morten Mørup   +3 more
doaj   +1 more source