Results 111 to 120 of about 8,375,026 (338)
ABSTRACT Background Head and neck cancers (HNCs) are too often diagnosed at advanced stages when outcomes are poor. Additionally, robust tools for the early detection of recurrence remain elusive. These gaps drive interest in so‐called liquid biopsy approaches for HNC detection, prognostication, and surveillance.
Patricia J. Brooks, Scott V. Bratman
wiley +1 more source
Comparison of the in vitro transforming activities of human papillomavirus types. [PDF]
Alan Storey+5 more
openalex +1 more source
Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert+3 more
wiley +1 more source
Quantitative keratinocyte assay detects two biological activities of human papillomavirus DNA and identifies viral types associated with cervical carcinoma. [PDF]
Richard Schlegel+3 more
openalex +1 more source
What's New? The rarity of acute lymphoblastic leukaemia and lack of available environmental data have made the role of environmental factors in genetic subtypes challenging to investigate. Here, the authors performed a CpG‐level analysis to investigate DNA methylation as an intermediate mechanism between environmental risk exposures and acute ...
Jessica R. Saville+5 more
wiley +1 more source
A point mutational analysis of human papillomavirus type 16 E7 protein [PDF]
Charles G. Edmonds, Karen H. Vousden
openalex +1 more source
What's New? While artificial intelligence (AI) can potentially support clinical decision‐making in recurrent head and neck squamous cell carcinoma (HNSCC), its reliability and accuracy require extensive investigation. Here, the performance of ChatGPT‐4 as a decision‐support tool for staging and treatment planning in HNSCC was assessed. The tool was 83%
Danfang Yan+9 more
wiley +1 more source
Presence of highly oncogenic human papillomavirus in the oral mucosa of asymptomatic men
Objectives: The aim of this study was to identify highly oncogenic forms of human papillomavirus in the oral mucosa of asymptomatic men. Methods: In this study, we analyzed samples of exfoliated cells from the oral cavity of 559 asymptomatic men.
Ana Paula Machado+8 more
doaj
What's New? Screening, combined with treatment of precancerous lesions, is key to preventing anal cancer. Here, the authors compare different screening algorithms. The International Anal Neoplasia Society recommends swab‐based screening as a first step, either cytology‐based or HPV‐based, and digital anal rectal exam (DARE).
Kirsten Rozemeijer+6 more
wiley +1 more source
Human papillomavirus type 16 DNA-induced malignant transformation of NIH 3T3 cells [PDF]
S Yasumoto+3 more
openalex +1 more source