Results 121 to 130 of about 260,495 (313)

Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert   +3 more
wiley   +1 more source

Predictive biomarkers for regression in women undergoing active surveillance for cervical intraepithelial neoplasia grade 2: A prospective multicenter study in Italy

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Cervical intraepithelial neoplasia grade 2 (CIN2) lesions can spontaneously regress, especially in women aged under 30. Better predictive biomarkers are needed to improve risk stratification for active surveillance. This prospective multicenter cohort study evaluated HPV genotyping, p16/ki67 expression, and FAM19A4/miR124‐2 methylation ...
Helena Frayle   +32 more
wiley   +1 more source

Comparison of the in vitro transforming activities of human papillomavirus types. [PDF]

open access: bronze, 1988
Alan Storey   +5 more
openalex   +1 more source

Evaluation of TypeSeq, a Novel High-Throughput, Low-Cost, Next-Generation Sequencing-Based Assay for Detection of 51 Human Papillomavirus Genotypes. [PDF]

open access: yes, 2019
BackgroundHuman papillomaviruses (HPV) cause over 500 000 cervical cancers each year, most of which occur in low-resource settings. Human papillomavirus genotyping is important to study natural history and vaccine efficacy. We evaluated TypeSeq, a novel,
Boland, Joseph   +20 more
core   +1 more source

Over one‐third of cancer cases and two‐fifths of cancer deaths in southern China are preventable: Insights from the latest representative population‐based cancer registry data and risk factor survey

open access: yesInternational Journal of Cancer, EarlyView.
What's New? This study quantified the cancer burden attributable to modifiable risk factors in Guangdong, the most populous and economically advanced province in southern China. By evaluating 15 modifiable risk factors, the study reveals that over one‐third of cancer cases and two‐fifths of cancer deaths in the region could potentially be prevented ...
Xiaolan Wen   +17 more
wiley   +1 more source

Associations of Atopobium, Garderella, Megasphaera, Prevotella, Sneathia, and Streptococcus with human papillomavirus infection, cervical intraepithelial neoplasia, and cancer: a systematic review and meta-analysis

open access: yesBMC Infectious Diseases
Background Lactobacillus spp. depleted and high diversity of vaginal microbiota is closely related to human papillomavirus infection and cervical cancer.
Yan Peng   +3 more
doaj   +1 more source

Molecular Identification of Human Papilloma Virus Genotypes in Patients with Cervical Cancer

open access: yesRevista Cubana de Investigaciones Biomédicas, 2020
Introduction: The principal cause of cervical cancer is human papillomavirus. In Camaguey population, molecular study about human papillomavirus does not exist.
Juan Carlos Piña Napal   +3 more
doaj  

Oral human papillomavirus (HPV) infection in men who have sex with men: prevalence and lack of anogenital concordance. [PDF]

open access: yes, 2015
To estimate the prevalence of oral detectable human papillomavirus (HPV) DNA in HIV-negative men who have sex with men (MSM) attending a sexual health clinic in London and concordance with anogenital HPV infection.
Beddows, S   +8 more
core  

Epidemiological approaches to evaluate clinical unmasking of HPV‐associated cervical lesions in the HPV vaccination era

open access: yesInternational Journal of Cancer, EarlyView.
Abstract HPV vaccination reduces the risk of developing HPV‐attributable cancers, including cervical cancer. However, an attenuation of HPV vaccine impact after the implementation of HPV vaccination may occur through clinical unmasking. Clinical unmasking is a distinct and complex phenomenon that arises in the absence of clinical interventions ...
Joseph E. Tota   +8 more
wiley   +1 more source

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