Results 141 to 150 of about 8,750,628 (402)

Cervical Cancer-Associated Human Papillomavirus 16 E7 Oncoprotein Inhibits Induction of Anti-Cancer Immunity by a CD4+ T Cell Dependent Mechanism [PDF]

, 2009
Attempts to develop therapeutic vaccines against cervical cancer have been proven difficult. One of the major causes of the failure is due to the use of the wrong mouse models based on transplantable tumours in testing the efficacy of vaccines.
Germain J. Fernando, Jie Zhong, Marion E. G. Brunck, Xiao Song Liu   +3 more
core   +2 more sources

Recombinant human papillomavirus nonavalent vaccine in the prevention of cancers caused by human papillomavirus

Infection and Drug Resistance, 2019
Human papillomavirus (HPV) types 16 and 18 cause 70% of cervical cancer cases globally. The nonavalent HPV vaccine (9vHPV) was licensed in 2014 and protects against the next five most common cancer-causing HPV types (HPV 31/33/45/52/58) after HPV 16/18 ...
Z. Toh, J. Kosasih, F. Russell, S. Garland, E. Mulholland, P. Licciardi   +5 more
semanticscholar   +1 more source

Th17 cells favor migration and invasiveness of cervical cancer cells under hypoxia in an IGF2BP2‐dependent manner

International Journal of Cancer, EarlyView.
What's New? Hypoxic regions and inflammatory Th17 cells in the tumor environment are both associated with poor prognosis in cervical cancer. However, synergistic mechanisms between hypoxia and Th17 cells remain elusive. This study demonstrated Th17–hypoxia‐driven mechanisms underlying cervical cancer progression.
Selina Gies, Maike Pohlers, Tanja Tänzer, Emmanuel Ampofo, Matthias W. Laschke, Moritz Schäfer, Yoo‐Jin Kim, Rainer Maria Bohle, Erich‐Franz Solomayer, Konrad Wagner, Martin Empting, Alexandra K. Kiemer, Barbara Walch‐Rückheim   +12 more
wiley   +1 more source

Human Papillomavirus Infection: Prevention, Barriers to Vaccination, and the Need for Education [PDF]

, 2016
While there is no known cure for HPV, prophylactic vaccination provides an effective method of primary prevention against HPV-related diseases. However, many females and males never receive the HPV vaccine as recommended.
Kessler, Theresa A
core   +2 more sources

Evidence for cross-protection but not type-replacement over the 11 years after human papillomavirus vaccine introduction [PDF]

, 2019
Examination of cross-protection and type replacement after human papillomavirus (HPV) vaccine introduction is essential to guide vaccination recommendations and policies.
Bernstein, David I., Brown, Darron, Covert, Courtney, Ding, Lili, Franco, Eduardo L., Kahn, Jessica A.   +5 more
core   +1 more source

Evidence of synergistic relationships between HIV and Human Papillomavirus (HPV): systematic reviews and meta‐analyses of longitudinal studies of HPV acquisition and clearance by HIV status, and of HIV acquisition by HPV status

Journal of the International AIDS Society, 2018
Observational studies suggest HIV and human papillomavirus (HPV) infections may have multiple interactions. We reviewed the strength of the evidence for the influence of HIV on HPV acquisition and clearance, and the influence of HPV on HIV acquisition.
K. Looker, Minttu M. Rönn, P. Brock, M. Brisson, M. Drolet, P. Mayaud, M. Boily   +6 more
semanticscholar   +1 more source

Cost‐effectiveness analysis of human papillomavirus (HPV) genotyping strategies for management of HPV‐positive women in cervical cancer screening

International Journal of Cancer, EarlyView.
What's New? Persistent infection with high‐risk human papillomavirus (HPV) causes most invasive cervical cancer cases, leading many countries to transition from cytology to primary HPV‐based screening. Despite the benefits, HPV‐based screening may also lead to unnecessary procedures, psychological burden, and strain on healthcare systems.
Kelsi R. Kroon, Johannes A. Bogaards, Johannes Berkhof   +2 more
wiley   +1 more source

Activation of the focal adhesion kinase signal transduction pathway in cervical carcinoma cell lines and human genital epithelial cells immortalized with human papillomavirus type 18 [PDF]

, 1997
Stephen J. McCormack, Scott E Brazinski, James L. Moore, Bruce A. Werness, D. Goldstein   +4 more
openalex   +1 more source

Human adenoviruses role in ophthalmic pterygium formation [PDF]

, 2015
Background: Ophthalmic pterygium is a common benign lesion of unknown origin and the pathogenesis might be vision-threatening. This problem is often associated with exposure to solar light. Recent evidence suggests that potentially oncogenic viruses such
Bazouri, M., Javid, N., Kelishadi, M., Kelishadi, M., Moradi, A., Tabarraei, A.   +5 more
core   +1 more source

Health care policy trial of primary human papillomavirus–based cervical screening in Denmark: Comparison of three triage algorithms

International Journal of Cancer, EarlyView.
What's New? Primary human papillomavirus (HPV)–based screening has shown superiority to cytology‐based screening in reducing cervical cancer risk in clinical trials. However, the benefit must be balanced with potential overdiagnosis/overtreatment.
Jeppe Bennekou Schroll, Jesper Bonde, Elsebeth Lynge, Marianne Waldstrøm, Petra Hall Viborg, Anna Frandsen, Rikke Holst Andersen, Susanne Merete Nielsen, Bettina Kjær Kristensen, Doris Schledermann, Berit Andersen, on behalf ofthe National Danish Cervical Cancer Screening Steering Committee   +11 more
wiley   +1 more source