Results 271 to 280 of about 263,787 (314)

Recent advancements in artificial intelligence‐powered cancer prediction from oral microbiome

open access: yesPeriodontology 2000, EarlyView.
Abstract Oral cancer is a major global health burden, ranking sixth in prevalence, with oral squamous cell carcinoma (OSCC) being the most common type. Importantly, OSCC is often diagnosed at late stages, underscoring the need for innovative methods for early detection.
Negin Soghli   +4 more
wiley   +1 more source

Exercise‐induced effects on atherogenesis and tryptophan catabolism via the kynurenine pathway in an HIV‐associated atherosclerosis mouse model

open access: yesExperimental Physiology, EarlyView.
Abstract A mouse model of HIV‐associated atherosclerosis (Tg26+/−ApoE−/−) exhibited increased plaque area compared with the ApoE−/− mouse, linked to elevated indoleamine 2,3‐dioxygenase (IDO) activity. IDO catalyses the conversion of tryptophan (TRP) into kynurenine (KYN), measured by the KYN‐to‐TRP ratio.
Marcus V. S. Rangel   +5 more
wiley   +1 more source

ZFP36 inhibits the pro‐apoptotic effects of transforming growth factor β1 on mitral valve interstitial cells via the GTP‐binding protein 6 pathway in mitral valve prolapse

open access: yesExperimental Physiology, EarlyView.
Abstract The objective of this work was to investigate the role of ZFP36 in mitral valve prolapse (MVP). Mitral valve and plasma were collected to assess the expression of ZFP36, transforming growth factor β (TGF‐β), collagen and elastin and apoptosis rates.
Meng Zhao   +9 more
wiley   +1 more source

The necessity and challenges of human papillomavirus testing for men. [PDF]

open access: yesFront Cell Infect Microbiol
Ren W   +7 more
europepmc   +1 more source

Predictive biomarkers for regression in women undergoing active surveillance for cervical intraepithelial neoplasia grade 2: A prospective multicenter study in Italy

open access: yesInternational Journal of Cancer, Volume 158, Issue 3, Page 587-596, 1 February 2026.
What's new? Cervical intraepithelial neoplasia grade 2 (CIN2) lesions can spontaneously regress, especially in women aged under 30. Better predictive biomarkers are needed to improve risk stratification for active surveillance. This prospective multicenter cohort study evaluated HPV genotyping, p16/ki67 expression, and FAM19A4/miR124‐2 methylation ...
Helena Frayle   +32 more
wiley   +1 more source

Harnessing viral footprints in circulating free DNA (cfDNA) for early cancer detection: A focus on liquid‐biopsy‐based screening

open access: yesInternational Journal of Cancer, Volume 158, Issue 3, Page 511-526, 1 February 2026.
Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah   +4 more
wiley   +1 more source

The prognostic value of cell‐free DNA dynamics during chemoradiotherapy in squamous cell carcinomas of the anus

open access: yesInternational Journal of Cancer, Volume 158, Issue 3, Page 790-798, 1 February 2026.
What's new? Chemoradiotherapy is the standard treatment for squamous cell carcinoma of the anus (SCCA). Toxicities linked to chemoradiotherapy, however, can negatively impact the quality of life, and biomarkers to distinguish which patients will benefit from treatment are lacking.
Anne Vittrup Jakobsen   +4 more
wiley   +1 more source

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