Results 141 to 150 of about 10,737,457 (301)

da Vinci Single‐Port Transoral Robotic Surgery in European Practice: Early Outcomes and Comparison With Transoral Laser Microsurgery

Clinical Otolaryngology, EarlyView.
ABSTRACT Objectives To report early outcomes following implementation of a da Vinci Single‐Port transoral robotic surgery (SP‐TORS) programme in the United Kingdom. To provide contextual benchmarking, outcomes were compared with a historical institutional cohort treated using transoral laser microsurgery (TLM). Design Retrospective institutional series
Matthew E. Ryan, Matthew Zammit, Kristijonas Milinis, Omar Ahmed, Rupali Sawant, Ava Gubbay, Somer Scott‐Clarkson, Harishanker Jeyarajan, Terry M. Jones, Mark Wilkie, Katharine Davies, Christopher Loh, Jason C. Fleming   +12 more
wiley   +1 more source

Cell cycle control and its modulation in HPV infected cells [PDF]

, 2010
A key effect of human papillomavirus (HPV) infection is to disrupt the normal cell cycle in order to subvert the cellular DNA replication machinery. Morphologically, condylomata induced by high and low risk HPV types cannot be distinguished and many ...
Lyman, Rachel C.
core  

Treatment Intensity and Delays Associated With Antibiotic Prescribing Prior to Head and Neck Cancer Diagnosis

Clinical Otolaryngology, EarlyView.
ABSTRACT Introduction Head and neck oncologic outcomes can be negatively affected by diagnostic delays. This study aimed to assess diagnostic delays and differences in treatment intensity associated with antibiotic prescribing prior to head and neck cancer.
Austin T. Armstrong, Jonathan Brewer, Jason Doherty, Joanne Salas, Ronald J. Walker, Sean T. Massa   +5 more
wiley   +1 more source

Merkel cell carcinoma: an updated guide for pathologists

Histopathology, EarlyView.
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley   +1 more source

Distinct Rb expression pattern in HPV‐associated neuroendocrine carcinomas of the uterine cervix

Histopathology, EarlyView.
Most uterine cervical neuroendocrine carcinoma (UCNEC) cases are HPV‐associated and are characterized by partial loss of Rb, p16 overexpression, and cyclin D1 negativity. A minority of UCNECs exhibit a distinct pattern, characterized by HPV negativity, retained Rb expression, focal p16 expression and cyclin D1 positivity.
Nobuko Yasutake, Misato Komamizu, Takeshi Iwasaki, Ryosuke Kuga, Tomomi Manako, Mikiko Hashisako, Rina Jiromaru, Tomoko Sho, Norihito Yuge, Kenzo Sonoda, Hideaki Yahata, Yoshinao Oda, Hidetaka Yamamoto   +12 more
wiley   +1 more source

Poliovirus receptor (CD155) expression in gastric‐type adenocarcinoma of the cervix compared with human papillomavirus–associated and other human papillomavirus–independent adenocarcinomas

Histopathology, EarlyView.
Poliovirus receptor (PVR, CD155) was universally expressed in gastric‐type cervical adenocarcinoma (GAS), correlating with PD‐L1 positivity and aggressive pathological features, and was associated with poorer survival. These findings identify PVR as a marker of GAS's aggressive, immunologically distinct phenotype and nominate the PVR/TIGIT axis as a ...
Kyosuke Kamijo, Hirofumi Ando, Shiori Oshima, Shiho Asaka, Manaka Shinagawa, Yoshinori Sato, Ryoichi Asaka, Marina Fujioka, Natsuki Uchiyama, Yusuke Yokokawa, Masako Nakajima, Koichi Ida, Yukiko Kusama, Takeshi Uehara, Yaeko Kobayashi, Tsutomu Miyamoto   +15 more
wiley   +1 more source

A longitudinal study of avian pox in a small passerine, the Dunnock (Prunella modularis)

Ibis, EarlyView.
Long‐term, longitudinal studies of disease in wild bird populations are rare. Diseases are important determinants of bird survival and may spill‐over into other species including livestock and, in some cases, humans. Avian pox is a globally distributed disease, resulting from infection by viruses in the genus Avipoxvirus (APV).
Denise C. Wawman, Steven R. Fiddaman, Becki Lawson, Maria D. Christodoulou, Ben C. Sheldon, Adrian L. Smith   +5 more
wiley   +1 more source

Male genital lichen sclerosus

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Male genital lichen sclerosus is driven by chronic, occluded exposure of susceptible genital epithelium to urine, rather than infection or autoimmunity. This review synthesizes clinical, anatomical and molecular evidence showing how microincontinence and occlusion initiate inflammation, fibrosis and carcinogenesis, and explains the curative effect of ...
Georgios Kravvas, Rory Barry, Richard E. Watchorn, Christopher B. Bunker   +3 more
wiley   +1 more source

Current Perspectives on Human Papillomavirus (HPV): Strengthening the Evidence Base for Global Elimination

The infection with human papillomavirus (HPV) represents one of the most salient public health challenges on a global level [...
Tomislav Meštrović, Vanja Kaliterna
core   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source