Results 51 to 60 of about 12,861,632 (309)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

On-Ice and Off-Ice Linear Sprint Performance Across Competitive Levels in Ice Hockey Players: Insights from Continuous Velocity Profiling

open access: yesSports
Linear speed is a key performance determinant in ice hockey, yet no studies have compared continuous on-ice and off-ice velocity profiles across multiple competitive levels.
Dominik Jablonka   +5 more
doaj   +1 more source

A Systematic Review with Meta-Analysis on the Effects of Plyometric-Jump Training on the Physical Fitness of Combat Sport Athletes

open access: yesSports, 2023
We aimed to assess the athletic performance changes in combat sport athletes (CoSAs) after plyometric-jump training (PJT), compared to control conditions, through a systematic review with meta-analysis.
Alex Ojeda-Aravena   +5 more
doaj   +1 more source

The effects of human disturbance on the activity of wild reindeer in different physical condition

open access: yesRangifer, 1988
We compared two Norwegian wild reindeer herds, Knutsho in excellent physical condition and Hardangervidda in poor physical condition, before and during disturbance by human hunters in order to test whether physical condition effected foraging strategy under stress.
Skogland, Terje, Grøvan, Beate
openaire   +4 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Attention and Awareness: Visual Psychophysics and Aversive Conditioning in Humans [PDF]

open access: yes, 2006
We studied the neuronal correlates of consciousness by characterizing the role of attention and awareness in three psychophysical experiments. First, we investigated the role of visual awareness in the formation of afterimages, phenomena believed to ...
Tsuchiya, Naotsugu
core   +1 more source

Effects of Different Intensities of Post-Activation Performance Enhancement Protocols on Repeated Sprint Ability in Male Soccer Players: A Randomized Crossover Trial

open access: yesApplied Sciences
(1) Background: Enhancing repeated sprint ability (RSA) is critical to soccer performance. Post-activation performance enhancement (PAPE) protocols, particularly those utilizing heavy resistance preloading, have shown promise in improving RSA.
Mustafa Şakir Akgül   +6 more
doaj   +1 more source

Body composition adaptations to lower-body plyometric training: a systematic review and meta-analysis

open access: yesBiology of Sport, 2021
The aim of this meta-analysis was to explore the effects of plyometric jump training (PJT) on body composition parameters among males. Relevant articles were searched in the electronic databases PubMed, MEDLINE, WOS, and SCOPUS, using the key words ...
Rodrigo Ramirez-Campillo   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The Acute Effect of Different Cluster Set Intra-Set Rest Interval Configurations on Mechanical Power Measures During a Flywheel Resistance Training Session

open access: yesSports
The aim of this study was to compare the acute effect of three cluster set (CS) intra-set rest intervals (15 s, 30 s, and 45 s) on mechanical performance measures during a flywheel resistance training session.
Shane Ryan   +4 more
doaj   +1 more source

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