Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
iScienceSummary: Hypoxemia is common during sedated gastrointestinal endoscopy (SGIE), especially in overweight and obese patients, yet the effectiveness of nasopharyngeal airways (NAs) for prevention remains unclear.
Hai-Ding Zou +7 more
doaj +1 more source
Research in medical education [PDF]
, 2009 The year 2009 saw a number of developments in Medical Education in Malta that were initiated as a result of a commitment to revising the medical curriculum in order to meet the challenges in medical education.
Vassallo, Josanne
core
Human GM-CSF primes neutrophils for enhanced oxidative metabolism in response to the major physiological chemoattractants [PDF]
, 1987 RH Weisbart, L Kwan, DW Golde, JC Gasson
openalex +1 more source
A Flexible and Biodegradable Piezoelectric‐Based Wearable Sensor for Non‐Invasive Monitoring of Dynamic Human Motions and Physiological Signals [PDF]
, 2023 Mohsin Ali +5 more
openalex +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Efficacy of Inquiry-Based and “Cookbook” Labs at Human Physiology Lessons at University Level - Is There an Impact in Relation to Acquirement of New Knowledge and Skills? [PDF]
, 2020 Lukáš Rokos, Radka Závodská
openalex +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Estimation of tilapia fish quality in Lake Edku through physiological analyses regarding trace element accumulation, antioxidant enzymes, proximate composition, and human health risk assessment as the ultimate consumer [PDF]
, 2021 Heba H. Abdel-Kader, Mohamed H. Mourad
openalex +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source