Results 121 to 130 of about 720,906 (256)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Urine cf-nucleosomes: A non-invasive window into human physiology and disease. [PDF]

Cell Genom
Lotem M, Sharkia I, Azria B, Harpenas E, Ormianer M, Rosen H, Falick-Michaeli T, Friedman N.   +7 more
europepmc   +2 more sources

Ancient DNA and human physiology. [PDF]

Physiology (Bethesda)
Bayarsaikhan M, Boyle MJ, Demers PV, Habeck Iv EW, Romeyer-Dherbey JH, Silverman S, Massilani D.   +6 more
europepmc   +1 more source

Editorial: Rhythmic Patterns in Neuroscience and Human Physiology. [PDF]

Front Hum Neurosci, 2022
Dominici N, Iosa M, Vannozzi G, De Bartolo D.   +3 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Microproteins in Human Physiology and Pathology. [PDF]

Biochemistry
Du Z, Trifiro FA, Brunet MA, Prensner JR.   +3 more
europepmc   +1 more source

Independent effects of acute normobaric hypoxia and hypobaric hypoxia on human physiology. [PDF]

Sci Rep, 2022
Rosales AM, Shute RJ, Hailes WS, Collins CW, Ruby BC, Slivka DR.   +5 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Controversial effects of metformin on human physiology and pathophysiology. [PDF]

Front Pharmacol
Fang S, Liu Q, Lu Y, Zhang J.
europepmc   +1 more source

Leftovers of viruses in human physiology. [PDF]

Brain Struct Funct, 2021
Arneth B.
europepmc   +1 more source